Use of Antiandrogens as Therapeutic Agents in COVID-19 Patients
December 2022
in “
Viruses
”
Research cited in this study
8 / 8 resultsresearch COVID-19: Pulmonary and Extra Pulmonary Manifestations
The study highlighted that COVID-19 was not solely a respiratory disease but a multisystem disease with both pulmonary and extrapulmonary manifestations. It emphasized that while some patients were asymptomatic, symptomatic cases could present with mild to severe pulmonary symptoms or extrapulmonary symptoms such as gastroenteritis, fever, or vomiting. Severe cases could lead to complications like acute kidney injury, heart failure, and venous thromboembolic events due to high viral load or cytokine storm. The study underscored the importance of recognizing these manifestations for early diagnosis and controlling the spread of the infection.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Do Anti-androgens Have Potential as Therapeutics for COVID-19?
research 5-Alpha-Reductase Inhibitors Are Associated With Reduced Frequency of COVID-19 Symptoms in Males With Androgenetic Alopecia
5-alpha-reductase inhibitors may reduce COVID-19 symptoms in bald males.
research Sex Differences in SARS-CoV-2 Infection Rates and the Potential Link to Prostate Cancer
Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.
research Revising the Role of the Androgen Receptor in Breast Cancer
The document concludes that targeting the androgen receptor may be a promising breast cancer treatment, especially for certain types.
research Visualizing Androgen Receptor Activity in Male and Female Mice
Androgen receptors are active in many tissues of both male and female mice, not just reproductive organs.
research Antiandrogen Therapy for Androgenetic Alopecia
Antiandrogen therapy helps treat genetic hair loss.