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This study identified CD201+ fibroblast progenitors in mouse skin that regulate wound healing through differentiation into specialized cell types, with retinoic acid and hypoxia influencing this process.

Regenerative medicine shows promise for aesthetic surgery, but needs more research for widespread use.

This study found multipotent progenitors in sweat ducts that become unipotent after sweat gland development, highlighting distinct regenerative capabilities in adult glandular skin stem cell populations.

This review discusses the advancements in biologic skin substitutes for wound treatment and their potential in enhancing cutaneous regeneration but reports no new clinical results.

This review discusses the modern approach of skin tissue engineering for chronic wound treatment, focusing on bioengineered artificial skin substitutes and assessing innovations in biomaterials and cell use; it reports no new clinical results.

This review discusses the use of platelet-rich plasma in cosmetic surgery, highlighting its expanding applications and promising potential in aesthetic treatments, but reports no new empirical findings.

Inhibiting PGD2 and using dermal papilla cells may improve skin and hair regeneration.

This chapter reviews the use of electrospun matrices in creating tissue-engineered skin substitutes and reports no new clinical results; it emphasizes the need for a cell-friendly microenvironment.

This chapter reviews traditional and tissue-engineered treatments for skin defects and discusses advances in bioengineered skin constructs, but it presents no new experimental results.

This review discusses the role of pharmacological sciences in advancing regenerative medicine technologies but reports no new experimental findings; the authors advocate for increased pharmacologist involvement to drive innovations.

This article proposes several potential approaches for scar prevention and therapy, including anti-transforming growth factor-β strategies and tissue-engineered skin, but reports no new clinical results.

This review discusses the role of stem cells and tissue engineering in regeneration and transplantation, emphasizing the need for advanced technologies to improve treatments for injuries and disabilities, but reports no new results.

This review discusses the shared molecular and cellular processes in the early development stages of skin appendages like hair follicles, teeth, and mammary glands, reporting no new results.

This review discusses the distinct roles and surprising developmental flexibility of multiple somatic stem cell types in tissue maintenance and repair, reporting no new results but highlighting emerging questions about their regulation and origins.

This article reviews current strategies and advancements in regenerating skin appendages and sensory nerves in tissue-engineered skin, highlighting the challenge of restoring skin sensations like pain, temperature, and touch to improve patients’ quality of life.

This research suggests that targeting the HIF-1α pathway via PHD inhibitors may enable regeneration similar to amphibians in mammals, potentially fast-tracking regenerative therapies from mice to humans.

This study found that an enzymatic digestion method for isolating hair follicle stem cells from scalp specimens yielded 5.3 times more epithelial cells than explant cultures, while supporting comparable cell functionality, offering a promising technique for tissue engineering and regenerative medicine.

This study explores the potential roles of exosomes in anti-aging applications, highlighting their ability to modulate inflammation, promote tissue regeneration, and transfer bioactive molecules to rejuvenate aging tissues and reverse cellular dysfunction.

This review discusses the potential regulation of signal transduction pathways by microRNAs in animal cells, aiming to identify biological processes that may be influenced by miRNA-mediated regulation, but it reports no new experimental outcomes.

This review summarizes fundamental concepts and recent advancements in hair follicle biology, including insights from mouse models into broader molecular and cellular processes relevant to regeneration and development.

This study found that deleting the ATR gene in adult mice led to rapid onset of age-related traits such as hair graying and osteoporosis through reduced regenerative capacity.

This review discusses the role of androgens in the progression of cardiovascular disease and explores novel therapeutic targets without reporting new clinical results.

This study found that differentiated airway epithelial cells can revert into functional stem cells in vivo, suggesting a more general role for this dedifferentiation process in tissue regeneration in higher vertebrates.

This article reviews the biology of epithelial stem cells and their role in tissue self-renewal, maintenance, and regeneration, and it highlights the clinical implications of understanding their signaling pathways, but it presents no new clinical findings.

This study developed molecular signatures for dermal papilla cells and their niche, uncovering novel signaling regulators and genes linked to hair disorders, which may inform future hair development research.

This review discusses experimental data, technologies, and genetic factors related to stem cell niches, highlighting their role in tissue regeneration and diseases, but reports no new results.

This study found that super-enhancers are essential for hair follicle stem cell identity, lineage commitment, and plasticity in mice, with SOX9 being a key regulator of these chromatin dynamics.

This review explores how preconditioning mesenchymal stromal cells can impact their secretome's therapeutic potential in regenerative medicine, emphasizing immunomodulatory and regenerative functions, but provides no new clinical results.

This review discusses the protective roles of skin-resident immune cells in maintaining tissue homeostasis and facilitating wound healing, but reports no new experimental findings.

This review explores fibroblast heterogeneity in the mammalian dermis and suggests potential therapeutic applications by targeting fibroblast subtypes, but reports no new experimental results.