1 citations
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March 2024 in “Brain Imaging and Stimulation” This study reported that a 3D-printed LED photobiomodulation device is technically and financially feasible, but requires further experimental and clinical testing before being used in human healthcare.
3 citations
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June 2021 in “Frontiers in genetics” This study found that STAT3 directly inhibited the activity of the sheep FST gene promoter, consequently reducing cell proliferation and promoting a better understanding of hair follicle development mechanisms.
28 citations
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December 2002 in “Der Hautarzt” TrichoScan accurately measures hair growth and loss, showing increased hair counts and thickness with treatment.
33 citations
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May 2017 in “Journal of Clinical Oncology” This phase I study reported that ETC-159, targeting Wnt signalling, showed tolerable safety profiles at doses that inhibit its pathway, though bone turnover markers increased, warranting early and regular monitoring. No tumor responses were observed, but two patients achieved stable disease for several cycles.
18 citations
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April 2016 in “Molecular Genetics and Genomics” This study suggests that thymosin beta 4 may regulate hair growth by influencing VEGF and MMP-2 levels through the Wnt/β-catenin/Lef-1 signaling pathway in mouse models.
18 citations
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March 2015 in “Journal of Investigative Dermatology” In this study, silencing BMAL1 and PER1 genes increased melanogenic activity in follicular and epidermal melanocytes, suggesting that peripheral circadian clocks may regulate melanin pigmentation.
1 citations
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February 2022 in “Clinical, Cosmetic and Investigational Dermatology” In this study, researchers found that the thyroxine receptor agonist TDM10842 accelerated the onset of anagen, a hair growth phase, in C3H mice, potentially through activation of the Wnt/beta-catenin and Hedgehog pathways, with Pclaf playing a key role in this process.
October 2024 in “Endocrinology Insights” In this study, researchers found that both the EU-TIRADS and Bethesda systems exhibited high specificity but suboptimal sensitivity for predicting thyroid nodule malignancy in patients who underwent surgery, with Bethesda system showing particularly high specificity in this postoperative population.
June 2023 in “jurnal veteriner” In this study, Typhonium flagelliforme leaf-ethanolic extract combined with natural interferon was observed to stabilize body weight, inhibit tumor growth, and reduce mitosis, angiogenesis, and certain protein expressions in carcinogen-induced tumors in female mice, suggesting potential antitumor effects.
15 citations
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December 2014 in “PLoS ONE” This study identifies iRhom2 as a crucial regulator of hair follicle differentiation, showing that the iRhom2Uncv mutation leads to dysplasia and reduced TACE maturation, resulting in a hairless phenotype in mice.
4 citations
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May 2022 in “PeerJ” This study suggests that melatonin promotes hair growth-related properties in DP cells by activating the AKT/GSK3β/β-catenin signaling pathway through melatonin receptors in a 3D spheroid culture system.
April 2016 in “Journal of Investigative Dermatology” Mutations in the TSPEAR gene cause a new form of ectodermal dysplasia affecting hair and tooth development.
215 citations
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November 2000 in “Journal of Investigative Dermatology” This study found that the tetracycline-regulated transcription system effectively controls conditional gene expression in the mouse epidermis, allowing suppression and activation of specific genes with doxycycline.
April 2019 in “Biometrics” This discussion reviews a hybrid phase I-II/III clinical trial design that enables dose re-optimization in phase III, but reports no new findings.
October 2020 in “Stem cells” This study highlights a novel connection between the DNMT3B enzyme, metabolic flux, and the self-renewal and differentiation of human embryonic stem cells.
13 citations
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June 2012 in “Journal of Dermatological Case Reports” This report describes an 8-year-old male with trichotillomania, confirmed by trichoscopy showing characteristic hair damage and patterns.
10 citations
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January 1997 in “Dermatology” This case report details two siblings with trichothiodystrophy, identifying reduced hair sulfur content as essential for diagnosis despite varied symptoms complicating recognition.
5 citations
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May 2023 in “European Journal of Human Genetics” This study found that mutations in the TULP3 gene are associated with progressive degeneration of the liver, kidney, and heart in adults, highlighting the importance of early detection and management.
February 2006 in “Inpharma Weekly” January 2026 in “Journal of Investigative Dermatology” This study found that 3D imaging may serve as a promising tool for objectively evaluating facial vitiligo repigmentation after treatment with upadacitinib.
January 2017 in “International journal of science and research” This review discusses treatment options for trichotillomania, focusing on cognitive-behavioral interventions and promising developments in combined pharmacotherapy and therapy approaches, but reports no new findings.
In this pilot study, researchers found that ex vivo treatment with topical melatonin reduced chemotherapy-induced apoptosis and DNA damage in hair follicle stem cells of human scalp cultures, suggesting melatonin's potential as a protective agent against taxane-induced permanent hair loss.
105 citations
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May 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that activation of the TRPV3 ion channel inhibits human hair growth by affecting hair follicles and outer root sheath keratinocytes.
August 2025 in “BMC Pharmacology and Toxicology” The LTF gene may help predict and manage nonspecific orbital inflammation.
January 2015 in “DukeSpace (Duke University)” This study found that deleting transferrin receptor 1 in specific mouse tissues led to varied lethal outcomes, demonstrating its diverse roles beyond iron uptake.
March 2004 in “Journal of The American Academy of Dermatology” This study found that the TrichoScan effectively measures hair growth changes, showing significant increases in hair counts and thickness in men with androgenetic alopecia after 6 months of using 5% minoxidil solution.
May 2010 in “OPAL (Open@LaTrobe) (La Trobe University)” This research discusses potential cancer vaccine strategies using cell-based and DNA vector-based approaches, and suggests targeting the v3 splice variant of thioredoxin reductase 1 to inhibit cancer cell motility and metastasis formation.
47 citations
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April 2012 in “The Plant Journal” This study found that mutations in phosphorylation sites on the PIN3 protein disrupt its phosphorylation and subcellular trafficking, affecting auxin transport and root growth in a cell-type-specific manner.
1 citations
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January 2022 in “Annals of Dermatology” In this case report, researchers identified a novel homozygous missense mutation in the MBTPS2 gene associated with the mild form of IFAP syndrome in a 7-year-old boy.
400 citations
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January 2014 in “British Journal of Sports Medicine” This consensus statement discusses guidelines for screening, diagnosing, and treating the Female Athlete Triad, and introduces a risk stratification system to assist healthcare providers with sports participation decisions.