Characterization of the Role of Transferrin Receptor 1 in the Intestinal Epithelium, Pancreas, and Skin

    January 2015 in “ DukeSpace (Duke University) ”
    Alan Chen
    Studysummary This study found that deleting transferrin receptor 1 in specific mouse tissues led to varied lethal outcomes, demonstrating its diverse roles beyond iron uptake.
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    Research cited in this study 6

    1. Epidermal Wnt/β-Catenin Signaling Regulates Adipocyte Differentiation via Secretion of Adipogenic Factors Proceedings of the National Academy of Sciences of the United States of America · 2014
    2. More Than One Way to Skin Genes & Development · 2008
    3. Stratum-Specific Expression of Human Transferrin Receptor Increases Iron in Mouse Epidermis Journal of Investigative Dermatology · 2006
    4. Location and Phenotype of Human Adult Keratinocyte Stem Cells of the Skin Differentiation · 2004
    5. Transient Activation of Beta-Catenin Signaling in Adult Mouse Epidermis Induces New Hair Follicles, Continuous Activation Maintains Tumors Development · 2004
    6. Expression of Keratin K14 in the Epidermis and Hair Follicle: Insights Into Complex Programs of Differentiation The Journal of Cell Biology · 1989