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research FLCN regulates transferrin receptor 1 transport and iron homeostasis

1 citations , January 2021 in “Journal of biological chemistry/The Journal of biological chemistry”

This study found that loss of the folliculin protein delays transferrin receptor recycling, leading to iron deficiency and suggesting a role in the mechanisms of Birt-Hogg-Dubé syndrome.

research Characterization of the Role of Transferrin receptor 1 (Tfr1) in the Intestinal Epithelium, Pancreas, and Skin

January 2015 in “DukeSpace (Duke University)”

This study found that deleting transferrin receptor 1 in specific mouse tissues led to varied lethal outcomes, demonstrating its diverse roles beyond iron uptake.

research Stratum-Specific Expression of Human Transferrin Receptor Increases Iron in Mouse Epidermis

14 citations , January 2006 in “Journal of Investigative Dermatology”

This study found that controlling transferrin receptor expression effectively regulates iron content in the epidermis and hair of transgenic mice.

research Epidermal growth factor and transferrin receptor expression in human embryonic and fetal epidermal cells

10 citations , December 1990 in “Archives of Dermatological Research”

research Efficient In Vitro Transfection of Human Keratinocytes with an Adenovirus-Enhanced Receptor-Mediated System

16 citations , April 2000 in “Journal of Investigative Dermatology”

The study reports that the AVET system showed higher efficiency in transfecting cultured human keratinocytes compared to SuperFect and PrimeFector, with AVET reaching levels of enzyme activity similar to normal cells in keratinocytes from lamellar ichthyosis patients.

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community PYRILUTAMIDE PHASE 3 RESULTS : No statistical significance

124 upvotes 2 years ago

The phase 3 trial results for Pyrilutamide showed no significant difference from the control treatment in increasing hair count, leading to the company halting its development. Users discussed their disappointment and skepticism about hair loss treatments, with some mentioning other treatments like Minoxidil, Finasteride, and RU58841.

community I'm already DOING EVERYTHING!!!

26 upvotes 5 years ago

A 26 year old female dealing with hair loss who is considering treatments such as Spiro, minoxidil and finasteride. Other potential solutions mentioned are PRP treatment, a wig, and bio-identical estrogen combined with bica.

community Female, 27 years old, shedding/ balding despite being on what is considered to be a effective treatment plan for AGA. Considering Dut (oral) . Please help.

in Finasteride/Dutasteride 27 upvotes 1 year ago

A 27-year-old woman with androgenic alopecia is losing hair despite using oral minoxidil and spironolactone, and is considering dutasteride. She is exploring causes like stress and medication side effects, planning tests, and considering treatment changes.

community new hair out of nowhere 3 weeks post HT! no meds, no vitamins, just growth

142 upvotes 7 months ago

After a hair transplant, the user noticed unexpected new hair growth without using medications or vitamins. Many advised starting treatments like minoxidil and finasteride to maintain the results and prevent future hair loss.

community Why do we get bald from evolutionary perspective

in Chat 213 upvotes 1 year ago

Baldness is not an evolutionary disadvantage because it occurs after reproductive age. Treatments like Minoxidil and Finasteride are used for androgenetic alopecia but don't address the root cause.

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