16 citations
,
September 2006 in “The Journal of Immunology” This study identified that mouse MILL1 and MILL2 are glycoproteins distinct from human MICA/B, primarily due to their association with β2-microglobulin and TAP-independent surface expression.
11 citations
,
October 2004 in “Journal of Experimental Biology” This review discusses the lasting impact of a 1951 J. Exp. Biol. paper on skin grafting methods and transplantation tolerance, which significantly influenced the field of transplantation biology.
2 citations
,
November 1996 in “Transplantation” This study found that intrathymic injection of recipient-type splenocytes into donor rats, combined with antilymphocyte antiserum, effectively prevented graft-versus-host disease for up to 300 days.
1 citations
,
January 2024 in “Nature communications” This study found that stimulating toll-like receptor 5 via mucosal delivery of a flagellin-containing fusion protein effectively extended lifespan and enhanced healthspan in mice, including improved bone density and cognitive capacity.
1 citations
,
March 2012 in “Revue neurologique” This study reports that both a 9-month-old with phenylketonuria on a phenylalanine-free diet and mice on a deficient diet exhibited severe health issues, highlighting the need for cautious dietary management.
1 citations
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April 2007 in “The FASEB Journal” In this study, D6D knockout mice showed severe deficiency in AA and DHA, leading to unexpected effects on skin health, fertility, and immune cell development.
May 2023 in “The Journal of Immunology” In this study of C3H/HeJ mice, researchers observed that alopecia areata is associated with the expansion of exhausted-memory CD8 T cells in multiple organs, with autoreactive activation not fully explained by known mechanisms, shedding light on the immunological dynamics underlying the condition.
December 2009 in “생명과학회지” This study found that thymosin β4 is highly expressed in multiple human tissues and may play a role in organ function and angiogenesis through co-localization with VEGF.
192 citations
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March 2017 in “Cell host & microbe” The researchers reported that hair follicle development and commensal microbe colonization promote the accumulation of regulatory T cells in neonatal skin, with the Ccl20-Ccr6 pathway playing a key role in this process.
May 2005 in “Cancer Research” This study found that over-expression of thymosin beta-4 in transgenic mice accelerated wound healing and hair growth, but did not affect tumor progression despite stimulating tumor metastasis.
7 citations
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January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that thymus transplantation in athymic mice resulted in T-cell-driven hair follicle depigmentation and loss, without multiorgan autoimmune disease, highlighting mechanisms of tissue-specific tolerance.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that targeting skin-infiltrated memory phenotype T cells could offer a new therapeutic approach to manage lymphopenia-related diseases like graft-versus-host disease and immune reconstitution inflammatory syndrome.
July 2026 in “Journal of Investigative Dermatology”
8 citations
,
January 2011 in “Experimental and Therapeutic Medicine” This review summarizes the characteristics of the peri-malignant melanoma stroma, indicating its potential role in early dermal metastatic migration and increased metastasis risk.
23 citations
,
May 2015 in “Science China Life Sciences” This article reviews how the microenvironment influences adult stem cell behavior and discusses strategies to enhance stem cell function but reports no new experimental results.
January 2026 in “Advances in Clinical and Experimental Medicine” This paper proposes a model integrating regulatory T cells and mesenchymal stem/stromal cells to enhance understanding of peripheral immune tolerance, suggesting their combined roles in immune regulation, autoimmunity pathophysiology, and potential MSC-based therapies.
12 citations
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December 2022 in “Current Protein and Peptide Science” This review discusses the molecular mechanisms and clinical applications of thymosin β4, highlighting its potential benefits for inflammation, wound healing, tumor metastasis, and other medical conditions but reports no new experimental results.
155 citations
,
May 2016 in “Nature communications” This study found that mouse skin CD4(+) memory T cells are in equilibrium with the circulation under steady state but increase in specific clusters in response to infection or inflammation.
11 citations
,
June 2020 in “FEBS Journal” This review discusses the regulation of myeloid cell networks in barrier tissues and how various factors influence immune homeostasis, but it reports no new experimental results.
January 2025 in “Annals of Thoracic and Cardiovascular Surgery” This case report describes a 55-year-old woman with alopecia areata whose condition improved rapidly and did not recur after the surgical resection of a thymoma, suggesting a potential immunological link between alopecia areata and thymoma that warrants further investigation.
November 2025 in “Journal of Investigative Dermatology” Certain immune cells in atopic dermatitis skin could be targeted for treatment.
August 2019 in “Journal of Invertebrate Pathology” This study observed that different alkaline buffers had a significant impact on the volume of liquid consumed by fall armyworm larvae, emphasizing the importance of measuring imbibed volumes to reduce dose errors in bioassays.
103 citations
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January 2011 in “Blood” This study found that thymus transplantation in infants with FOXN1 deficiency led to T-cell reconstitution and functional immunity, resolving serious infections and cytopenias.
January 2019 in “eScholarship (California Digital Library)” This study concluded that CNS1-dependent peripheral Tregs do not significantly impact type 1 diabetes in the NOD mouse model, with thymus-derived Tregs being the primary regulators.
67 citations
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January 2020 in “Cellular & Molecular Immunology/Cellular & molecular immunology” This review discusses the dual role of tissue-resident memory T cells in providing immune protection against infections and cancer and contributing to autoimmune skin disease pathology, without presenting new experimental results.
107 citations
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October 2022 in “Frontiers in Immunology” This bibliometric analysis examines the research landscape of T cells in atherosclerosis and identifies key trends and emerging research areas, highlighting the field's stabilization over the past decade.
13 citations
,
January 2021 in “Journal of Cellular and Molecular Medicine” This review discusses the roles and mechanisms of thymosin β4 in hair follicle growth and development but reports no new experimental findings; the authors emphasize the need for further research on its molecular pathways.
December 2014 in “Journal of Biomedical Research” In a mouse model of peripheral vascular disease, this study found that recombinant thymosin β4 treatment increased expression levels of certain proteins, promoting angiogenesis.
31 citations
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June 2011 in “Journal of the neurological sciences” In this case report, a patient with thymoma was observed to have four co-occurring paraneoplastic autoimmune disorders that improved after thymectomy, suggesting a possible link between thymoma and these conditions.
April 2023 in “Journal of Investigative Dermatology” This research explored the roles of various T cell types in chronic alopecia areata, finding that increased severity of lesions and hair loss may be linked to decreased lesional Foxp3+ Tregs, with a notable role for IL-17 and Th17 lymphocytes in the pathological process.