Adult Phenylketonuria: Neurological Manifestations and Evolutionary Modalities

    March 2012 in “ Revue neurologique ”
    L. Daelman, Claire Ewenzcyk, François Feillet, Zaïre Amoura, Ayman Tourbah, Frédéric Sedel
    Image of study
    TLDR Proper diet management is crucial for preventing severe symptoms in phenylketonuria.
    The document described a 9-month-old female with phenylketonuria who exhibited severe symptoms due to a phenylalanine-free diet, including erythema, desquamation, alopecia, keratomalacia, corneal perforation, failure to thrive, and prolonged diarrhea. These symptoms resolved with dietary correction. A subsequent mouse study with 63 mice on a phenylalanine-deficient diet showed similar issues such as weight loss, thymic reduction, and severe gastric dilation, but no brain or eye lesions. The study highlighted the need for careful dietary management in phenylketonuria to prevent such deficiencies and their severe manifestations.
    Discuss this study in the Community →

    Related Community Posts Join

    6 / 1000+ results

      community Is microneedling supposed to be a blood bath? 1mm dermastamp

      in Microneedling  41 upvotes 2 years ago
      The conversation is about someone experiencing a lot of bleeding from using a 1.0mm microneedling device for hair loss treatment and asking if it's normal. Various users suggest that the bleeding is excessive and recommend using shorter needles or less pressure, while others share their own microneedling practices with different needle lengths and no bleeding.

      community Posted this years ago but still getting questions!

      in Progress Pictures  326 upvotes 2 years ago
      The user successfully treated their hair loss using 1ml of minoxidil twice daily and dermarolling with a 1.5mm dermaroller once a week. They experienced noticeable results only after combining minoxidil with dermarolling, and they have not used finasteride.

      community Diffuse thinning is so brutal.

      in Styling  72 upvotes 2 years ago
      A 25-year-old with AGA experienced hair thinning and dandruff, stabilized with topical finasteride and minoxidil but saw minimal regrowth. They seek advice on styling and consider oral minoxidil and microneedling for denser hair.

      community What's up with everyone microneedling 1.5 mm per week?

      in Microneedling  52 upvotes 2 years ago
      The conversation is about microneedling for hair loss. The conclusion is that there are differing opinions on the depth and frequency of microneedling, with some studies suggesting positive results with 1.5mm depth once a week, while others prefer lower depths and less frequent sessions.

    Similar Research

    5 / 1000+ results