2 citations
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January 2022 in “Genetics Research” This study found that using hemocoagulase combined with platelet-rich plasma during total hip replacement surgery led to reduced perioperative blood loss and improved early joint range of motion in osteoarthritis patients.
115 citations
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August 2020 in “International Journal of Molecular Sciences” This systematic review indicates that a platelet-rich plasma concentration of 1.0 × 10^6 plt/μL may be optimal for tissue regeneration due to sufficient nutrition supply and effective growth factor diffusion in vivo.
January 2019 in “Kocaeli tıp dergisi” This study investigates the relationship between vitamin B12 levels and chronic telogen effluvium, reporting that the role of vitamin B12 in its pathogenesis remains unclear.
January 2023 in “Turk Dermatoloji Dergisi” In a single case study, researchers reported increased hair density using a trypsin-isolated cell suspension containing CD34 and CD200 positive cells for treating grade III androgenetic alopecia.
March 2026 in “Frontiers in Pharmacology” The study concluded that the Exprecell™ device for preparing anticoagulant-free f-PRF increases volume yield and simplifies the process while maintaining biological activity comparable to conventional methods, suggesting potential clinical utility.
12 citations
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June 2006 in “Anais Brasileiros de Dermatologia” This study reports that scalp biopsies in white adults usually have 16.5 hair follicles, primarily in the anagen phase, with male samples showing fewer follicular units but more fibrous tracts in certain areas.
3 citations
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October 2020 in “Case Reports in Veterinary Medicine” This case report describes the first documented occurrence of a free-floating left atrial thrombus in a dog, highlighting the lack of specific therapeutic strategies for treating intracardiac thrombi in dogs.
June 2023 in “Benha Journal of Applied Sciences” This study observed that female patients with chronic telogen effluvium had significantly lower levels of total thiol, thiol-disulphide, and disulphide compared to healthy controls, indicating a disruption in oxidative stress balance.
5 citations
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July 2024 in “Minerva Endocrinology” In this systematic review, an increase in hemoglobin and hematocrit was associated with testosterone therapy, especially within the first year, and factors like serum testosterone levels and therapy specifics were linked to erythrocytosis development, highlighting the need for further research to guide clinical practice.
7 citations
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August 2022 in “Nature communications” This study found that Thy1+ keratinocytes in the basal layer of the interfollicular epidermis play a crucial role in epidermal homeostasis and wound repair, with their ablation impairing these processes.
3 citations
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October 2025 in “Dentistry Journal” This study investigated different centrifugation systems and found that low-speed protocols and certified centrifuges produced better-quality platelet-rich fibrin and recommended using FDA-approved glass tubes for safe and effective regenerative outcomes.
January 2024 in “Universidad Peruana Cayetano Heredia Institutional Repository” In this in vitro study, simple centrifugation with calcium gluconate activation led to a significantly higher release of PDGF-BB in PRP compared to other methods, which may inform improved clinical PRP preparation protocols.
July 2024 in “The Journal of Dermatology” This article reported a case where a patient experienced both alopecia areata multiplex and chronic idiopathic thrombocytopenic purpura, an uncommon association, but it did not include specific results or detailed analyses.
2 citations
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April 2022 in “Indian Journal of Dermatology, Venereology and Leprology” This pilot study suggests that platelet-rich plasma may be a promising treatment for chronic telogen effluvium with good safety, and cost-effective preparation methods may be reliable alternatives to more expensive ones.
April 2026 in “Mathematics” This study used a probabilistic framework to show that platelet-rich plasma preparation results in significant variability in platelet dose due to factors like injected volume and concentration factor.
12 citations
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December 2020 in “Frontiers in Cell and Developmental Biology” This review covers the variability in methods for preparing platelet-rich plasma and reports no new clinical results, suggesting that this variability may contribute to inconsistent efficacy in clinical trials.
February 2021 in “INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH” This study found that women with telogen effluvium had significantly lower serum copper and zinc levels compared to controls, suggesting these deficiencies may be associated with the condition.
July 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” This study found that using exosomes derived from thrombin-pretreated umbilical cord mesenchymal stem cells significantly accelerated wound healing and improved skin regeneration in a mouse model, highlighting their potential as a cell-free therapy for skin injuries.
1 citations
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February 2023 in “Siriraj Medical Journal/San Sirirat” This study found that Thai males with androgenic alopecia displayed lower average hair density in the occipital scalp compared to other Asian populations, but higher than those with advanced AGA.
7 citations
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February 2009 in “Cell and tissue biology”
August 2024 in “Journal of Cosmetic Dermatology” This study investigates differences in nutritional status, vitamin, and mineral levels between individuals with telogen effluvium and a control group, aiming to understand the nutritional factors involved in this condition.
June 2025 in “International Journal of Science and Research (IJSR)” This study found that among 100 females with chronic telogen effluvium, approximately two-thirds had low levels of serum ferritin and vitamin D, while vitamin B12 deficiency was observed in only about one-third of the participants.
2 citations
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December 2015 in “Journal of dermatology research and therapy” This study compared serum zinc, vitamin B12, folic acid levels, iron metabolism, and thyroid function between chronic telogen effluvium patients and healthy controls, but it reports no specific clinical results.
September 2023 in “Journal of the American Academy of Dermatology” CTP-543 is generally safe for treating alopecia areata.
1 citations
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November 2016 in “International Society of Hair Restoration Surgery” Results are not reported for this abstract, which mentions that patients on antithrombotic therapy, important for preventing cardiovascular events, sometimes seek hair transplantation at the clinic.
7 citations
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September 2003 in “Journal of Investigative Dermatology” In this study, researchers found that thrombin may influence cyclic hair growth through its receptor PAR-1, although it does not seem to stimulate dermal papilla cell proliferation physiologically.
3 citations
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September 2006 in “Hair transplant forum international” This paper reflects on the challenges and progress in hair restoration, highlighting ongoing efforts for improvement but providing no new empirical findings.
15 citations
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April 2025 in “Journal of Clinical Medicine” This review reports that platelet-rich plasma may be more effective for musculoskeletal conditions when prepared with high platelet doses and low leukocyte content, but further trials are needed to confirm optimal formulations.
January 2022 in “International Journal of Medicine in Developing Countries” In this study, 35.4% of telogen effluvium patients showed ferritin deficiency and 34.2% had vitamin D deficiency, suggesting these should be included in TE screening; TSH testing should be individualized.
14 citations
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October 2015 in “PLoS ONE” This study found that keratins 5, 7, 8, and 19 are expressed in human trophoblast cells while vimentin is solely expressed in stromal-mesenchymal cells, aiding in placental cell type identification.