Anticoagulant-Free Preparation of Autologous Platelet-Rich Plasma (PRP) / Fluid Platelet-Rich Fibrin (f-PRF): A Pre-Clinical Comparative Performance Study

This review covers the diverse clinical applications of platelet-rich plasma in regenerative medicine but provides no new clinical results.

This systematic review and meta-analysis found that platelet-rich plasma (PRP) therapy is effective in increasing hair density and reducing hair loss for alopecia, with variations in response based on activation status.

In this systematic review and meta-analysis, the authors examined single-spin versus double-spin centrifugation protocols for PRP in patients with androgenic alopecia and found no significant difference in platelet concentration, hair density, or hair types between the protocols.

In this study, both Endo-RF subcision and the combination of Endo-RF subcision with PRP were shown to be safe and effective for improving post-acne scars, with the combination therapy potentially offering more desirable outcomes.

This study found that platelet-rich plasma therapy significantly improved hair density and reduced hair shedding in Vietnamese patients with androgenetic alopecia, with high patient satisfaction and minimal side effects.

This review suggests that combining platelet-rich plasma with microneedling may produce better hair restoration outcomes for androgenetic alopecia than using PRP injections alone, but calls for more standardized research.

This review discusses the potential of platelet-rich plasma in regenerative medicine and aging-related diseases but notes that clinical efficacy remains unclear due to varying study results and preparation inconsistencies.

This study compared fluid PRF and PRP for treating atrophic acne scars and found PRF to be more effective, particularly when combined with needling. Both treatments improved scars, but PRF showed higher therapeutic response, suggesting it as a superior alternative for acne scar treatment.

This review discusses the regenerative applications of platelet-rich plasma across various medical fields and reports no new clinical results, highlighting the need for further research into standardizing its preparation and use.

This review discusses various potential applications of platelet-rich fibrin in dermatology, but reports no clinical results and highlights the need for standardized protocols.