Local Injection Versus Topical Microneedling of Platelet-Rich Plasma for Androgenetic Alopecia: A Systematic Review

    March 2025 in “ Archives of Plastic Surgery ”
    Johannes Albert Biben, Ryan Reinhart, Karina Karina … Patricia Marcellina Sadikin
    Studysummary This review suggests that combining platelet-rich plasma with microneedling may produce better hair restoration outcomes for androgenetic alopecia than using PRP injections alone, but calls for more standardized research.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
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    Research cited in this study 22

    1. Androgenetic Alopecia: Therapy Update Drugs · 2023
    2. Use of Activated Platelet-Rich Plasma on Alopecia: A Systematic Review and Meta-Analysis Aesthetic Surgery Journal · 2023
    3. Comparison of Efficacy of Platelet-Rich Plasma With PRP Microneedling in Androgenetic Alopecia Cureus · 2022
    4. What's New in Therapy for Male Androgenetic Alopecia? American Journal of Clinical Dermatology · 2022
    5. Microneedling and Its Use in Hair Loss Disorders: A Systematic Review Dermatology and therapy · 2021
    6. The Inflammatory Component of Androgenetic Alopecia Journal of The American Academy of Dermatology · 2021
    7. Platelet Rich Plasma Application by Dermapen Microneedling and Intradermal Point-by-Point Injection Methods, and Their Comparison with Clinical Findings and Trichoscan in Patients with Androgenetic Alopecia Dermatologic Therapy · 2021
    8. Evaluation of Adding Platelet-Rich Plasma to Combined Medical Therapy in Androgenetic Alopecia Journal of Cosmetic Dermatology · 2021
    9. Platelet-Rich Plasma with Microneedling in Androgenetic Alopecia: Study of Efficacy of the Treatment and the Number of Sessions Required Journal of Cutaneous and Aesthetic Surgery · 2021
    10. Platelet-Rich Plasma: Evolving Role in Plastic Surgery Plastic and Reconstructive Surgery · 2020
    11. A Randomized Blinded Retrospective Study: The Combined Use of Micro-Needling Technique, Low-Level Laser Therapy, and Autologous Non-Activated Platelet-Rich Plasma Improves Hair Re-Growth in Patients with Androgenic Alopecia Expert Opinion on Biological Therapy · 2020
    12. Platelet-Rich Plasma as a Therapy for Androgenic Alopecia: A Systematic Review and Meta-Analysis Journal of Dermatological Treatment · 2020
    13. Platelet-Rich Plasma for Hair Restoration Facial Plastic Surgery Clinics of North America · 2020
    14. Novel Drug Delivery Approaches for the Management of Hair Loss Expert opinion on drug delivery · 2020
    15. Efficacy of Platelet-Rich Plasma and Concentrated Growth Factor in Treating Androgenetic Alopecia: A Retrospective Study Annals of maxillofacial surgery · 2020
    16. Dermoscopic Assessment of Microneedling Alone Versus Microneedling with Platelet-Rich Plasma in Cases of Male Pattern Alopecia: A Split-Head Comparative Study International Journal of Trichology · 2020
    17. Physiopathology and Current Treatments of Androgenetic Alopecia: Going Beyond Androgens and Anti-Androgens Dermatologic Therapy · 2019
    18. Safety Concerns When Using Novel Medications to Treat Alopecia Expert Opinion on Drug Safety · 2018
    19. Platelet-Rich Plasma with Microneedling in Androgenetic Alopecia Along with Dermoscopic Pre- and Post-Treatment Evaluation Journal of Cosmetic Dermatology · 2017
    20. Microneedling With Platelet-Rich Plasma Versus Microneedling With Topical 5% Minoxidil in Patients With Androgenetic Alopecia: A Comparative Study Journal of evolution of medical and dental sciences · 2017
    21. A Comparative Study of Microneedling with Platelet-Rich Plasma Plus Topical Minoxidil (5%) and Topical Minoxidil (5%) Alone in Androgenetic Alopecia International Journal of Trichology · 2017
    22. Micro-Needling Depth Penetration, Presence of Pigment Particles, and Fluorescein-Stained Platelets: Clinical Usage for Aesthetic Concerns Aesthetic Surgery Journal · 2016

    Related research 1

    1. Systematic Review of the Use of Platelet-Rich Plasma in Aesthetic Dermatology Journal of Cosmetic Dermatology · 2015