Local Injection Versus Topical Microneedling of Platelet-Rich Plasma for Androgenetic Alopecia: A Systematic Review

March 2025 in “ Archives of Plastic Surgery ”

Johannes Albert Biben, Ryan Reinhart, Karina Karina, Kuswan Ambar Pamungkas, Krista Ekaputri, Patricia Marcellina Sadikin

platelet-rich plasma microneedling androgenetic alopecia syringe injection PRP AGA

TLDR PRP with microneedling works better than injection for hair loss treatment.

This systematic review evaluates the effectiveness of platelet-rich plasma (PRP) administered via syringe injection versus a combination of topical PRP and microneedling for treating androgenetic alopecia (AGA). Out of 108 articles initially identified, 3 met the inclusion criteria for analysis. The findings suggest that the combination of PRP and microneedling yields superior results compared to direct syringe injection for AGA treatment. However, the review highlights the need for further high-quality studies with standardized protocols to confirm these results.

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Research cited in this study

22 / 22 results

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