research Identification of a Novel PNPLA1 Mutation in a Spanish Family with Autosomal Recessive Congenital Ichthyosis
A new gene mutation linked to a skin condition was found in a Spanish family.
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research Miniaturized Hairs Maintain Contact With the Arrector Pili Muscle in Alopecia Areata but Not in Androgenetic Alopecia: A Model for Reversible Miniaturization and Potential for Hair Regrowth
Miniaturized hairs stay connected to muscle in alopecia areata, allowing possible regrowth, but not in androgenetic alopecia.
research Roles of Steroid Sulfatase in Brain and Other Tissues
Steroid sulfatase is important for activating hormones that affect memory, brain function, and certain diseases, and could be a target for treating hormone-related disorders.
research Organ Regeneration Based on Developmental Biology: Past and Future
Scientists have made progress in growing mini-organs and regenerating parts of the skin, with plans to treat hair loss in a future trial.
research A Portable Electrospinner for Nanofiber Synthesis and Its Application for Cosmetic Treatment of Alopecia
A portable device can create nanofibers to improve the appearance of thinning hair better than commercial products.
research Quantitative Study of the Human Hair Follicle in Normal Scalp and Androgenetic Alopecia
Alopecia causes smaller hair follicles and affects growth-related structures.
research Long-Term Time-Lapse Multimodal Intravital Imaging of Regeneration and Bone Marrow-Derived Cell Dynamics in Skin
The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
research Rabson-Mendenhall Syndrome: Two Case Reports and a Brief Review of the Literature
The document concludes that Rabson-Mendenhall syndrome requires novel treatments for insulin resistance and emphasizes the importance of dental care in affected patients.
research Chapter 17: Selective Androgen Receptor Modulators (SARMs)
Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
research Investigation of Hair Shaft in Seborrheic Dermatitis Using Atomic Force Microscopy
Hair from people with seborrheic dermatitis is thicker scaled, more damaged, and thinner than healthy hair, and atomic force microscopy can help monitor the condition.
research Structural Characterization of Polymorphs and Molecular Complexes of Finasteride
Finasteride's molecular and crystal structures help develop new drug formulations.
research Engineering Cell-Derived Matrices: From 3D Models to Advanced Personalized Therapies
3D cell-derived matrices improve tissue regeneration and disease modeling.
research Molecular Modeling and Structural Characterization of a High Glycine–Tyrosine Hair Keratin Associated Protein
The 3D structure of a key hair protein was modeled, revealing specific helical structures and stabilization features.
research Spectrofluorimetric Study of Finasteride and Bovine Serum Albumin Interaction and Its Application for Quantitative Determination of Finasteride in Tablet Dosage Form
Method accurately measures finasteride in tablets using finasteride-BSA interaction.
research Screening of Synthetic and Natural Product Databases: Identification of Novel Androgens and Antiandrogens
Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
research Synthesis, Biological Evaluation and Molecular Docking of Avicequinone C Analogues as Potential Steroid 5α-Reductase Inhibitors
Certain compounds, especially those with a propionic substituent, could potentially be new treatments for hair loss and similar disorders.
research New Substrates for Stem Cell Control
New materials help control stem cell growth and specialization for medical applications.
research Bacillus/Trapa Japonica Fruit Extract Ferment Filtrate Enhances Human Hair Follicle Dermal Papilla Cell Proliferation via the Akt/ERK/GSK-3β Signaling Pathway
The extract from Bacillus/Trapa japonica fruit helps increase hair growth and could be a potential treatment for hair loss.
research Deficiency of the Human Cysteine Protease Inhibitor Cystatin M/E Causes Hypotrichosis and Dry Skin
Lack of cystatin M/E causes thin hair and dry skin.
research Transfollicular Drug Delivery: Current Perspectives
Transfollicular drug delivery is promising but needs more research to improve and understand it better.
research The Epithelial Stem Cell Niche in Skin
Skin's epithelial stem cells are crucial for repair and maintenance, and understanding them could improve treatments for skin problems.
research Encapsulation of Finasteride with Native and Modified Gamma-Cyclodextrins: Extensive Characterization of the Complexes
Finasteride's solubility improves with native y-CDs, enhancing hair loss treatment and reducing side effects.
research Skin Equivalent Assay: An Optimized Method for Testing Hair Growth Reconstitution Capacity of Epidermal and Dermal Cells
The 3D skin model is better for hair growth research and testing treatments.
research Plucked Human Hair Shafts and Biomolecular Medical Research
Human hair follicles may provide a noninvasive way to diagnose diseases and have potential in regenerative medicine.
research Core-Shell Nanocarriers Based on PEGylated Hydrophobic Hyperbranched Polyesters
The new nanocarriers improve how well water-insoluble drugs dissolve and allow for controlled drug release.
research Women's Skin Throughout Lifetime: Hormonal Impact and Disorders
Hormonal status significantly affects women's skin health throughout their lives.
research Evaluation of Donor Scars in Hair Restoration Using a New Cosmetic Surgery Scar Assessment Scale
The new Cosmetic Surgery Scar Assessment Scale (CSSAS) was found to be simple and effective in evaluating scars from hair restoration surgeries.
research Characterization of Human Ovarian Teratoma Hair Using AFM, FT-IR, and Raman Spectroscopy
Teratoma hair is similar to scalp hair but has a rougher surface and lower adhesive force.
research Morphological Characteristics and Notes of the Skin in Preclinical Toxicity Assessment
Skin structure complexity and variability are crucial for assessing skin toxicity in safety tests.
research Analysis of the Changes in Scalp Hair Angles: In Vivo and In Vitro Comparison Before and After Tumescence
Tumescent fluid increases scalp hair angles, which may improve hair transplant results and reduce surgeon fatigue.