research Regulation of Mitochondrial Oxidative Metabolism by Tumor Suppressor FLCN
The tumor suppressor gene FLCN affects mitochondrial function and energy use in cells.
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research Acne
Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.
research Replicative Stress, Stem Cells, and Aging
Maintaining DNA health in stem cells is key to preventing aging and tissue breakdown.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research Pathways to Inflammation: Acne Pathophysiology
Acne is caused by genetics, diet, hormones, and bacteria, with treatments not yet curative.
research Wnt Signaling Induces Epithelial Differentiation During Cutaneous Wound Healing
Wnt signaling is crucial for skin wound healing and reducing scars.
research Scalp Reconstruction Techniques After Oncologic Resection
Different scalp reconstruction methods work well, but the best one depends on the patient's unique needs.
research Menstrual Irregularity in Women with Acromegaly
Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.
research Sulfation of Minoxidil by Liver Sulfotransferase
Liver enzyme helps minoxidil work better for blood vessel relaxation.
research Anti-Acne Agents Attenuate FGFR2 Signal Transduction in Acne
Anti-acne medications may work by reducing the activity of a protein involved in acne development.
research The Paradox of p53: What, How, and Why?
The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.
research Surface Tension Guided Hanging-Drop: Producing Controllable 3D Spheroids of High-Passaged Human Dermal Papilla Cells and Forming Inductive Microtissues for Hair-Follicle Regeneration
Technique creates 3D cell spheroids for hair-follicle regeneration.
research Topical Application of a Protein Kinase C Inhibitor Reduces Skin and Hair Pigmentation
Applying a specific inhibitor lightens skin and hair color.
research MiR-218-5p Regulates Skin and Hair Follicle Development Through Wnt/β-Catenin Signaling Pathway by Targeting SFRP2
miR-218-5p helps skin and hair growth by targeting SFRP2 and activating a specific signaling pathway.
research Female Hirsutism: Pathophysiological Considerations and Therapeutic Implications
Excessive hair growth in women often has no known cause and is not linked to race or other hormonal symptoms.
research Finasteride for Female Androgenetic Alopecia
Finasteride increases hair density in female androgenetic alopecia, but individual results may vary.
research Skin Steroidogenesis in Health and Disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research Effects of Nitrendipine, Nifedipine, Verapamil, Phentolamine, Papaverine, and Minoxidil on Contractions of Isolated Rabbit Aortic Smooth Muscle
Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.
research 5α-Reduced Glucocorticoids: A Story of Natural Selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Drug Repositioning: Current Approaches and Their Implications in the Precision Medicine Era
Drug repositioning is becoming more targeted and efficient with new technologies, offering personalized treatment options and growing interest in the field.
research Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome
Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.
research Low Sex-Hormone Binding Globulin Levels in Young Women with Diffuse Hair Loss
Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.
research Network-Based Drug Repositioning: Approaches, Resources, and Research Directions
The document concludes that computational methods using networks and various data can improve the process of finding new uses for existing drugs.
research The Effect of Weight Loss and Treatment with Metformin on Serum Vaspin Levels in Women with Polycystic Ovary Syndrome
Weight loss and metformin don't significantly change vaspin levels in women with PCOS.
research The Balance of BMP6 and WNT10B Regulates the Telogen-Anagen Transition of Hair Follicles
BMP6 and Wnt10b control whether hair follicles are resting or growing.
research Effects of PNU157706, a Dual 5α-Reductase Inhibitor, on Rat Epididymal Sperm Maturation and Fertility
PNU157706 reduced rat sperm movement and fertility without affecting offspring health.
research Increased Levels of Prostaglandin-Like Material in Canine Blood During Arterial Hypotension Produced by Hydralazine, Dihydralazine, and Minoxidil
These drugs raise prostaglandin-like material in dog blood, possibly causing blood vessel widening.
research Exogenous Calreticulin Improves Diabetic Wound Healing
Applying calreticulin can speed up wound healing in diabetics.
research Office Diagnosis of Hair Shaft Defects
The document explains how to identify different hair problems using a microscope.
research Mammalian Fetal Organ Regeneration
Fetal wounds heal without scarring because of different biological factors, which could help improve adult wound healing.