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In this study using rats, finasteride-induced DHT deficiency led to morphological changes in seminiferous tubules, linked with altered junctional protein expression, potentially impairing fertility.

This review summarizes current knowledge on tight junctions in mammalian skin and their role in drug delivery and interaction with other barrier components, but reports no new experimental results.

This study demonstrated that tight junction barriers exist in human hair follicles but are less tight in hair follicle keratinocytes than in interfollicular keratinocytes, highlighting claudin-1's key role in follicle barrier function and growth.

In this study, researchers demonstrated that follicular tight junctions in porcine skin form a barrier to nanoparticle penetration, particularly in upper regions, which supports its use as a model for human skin.

This study found that administering testosterone to ovariectomized female rats decreased endometrial tight junction complexity and expression of specific proteins, potentially affecting embryo implantation.

In this study using tamoxifen-inducible claudin-1 knockout mice, researchers observed that tight junction barrier leakage induced stratum corneum barrier defects and skin inflammation, suggesting a possible cycle of barrier damage and inflammation in atopic dermatitis.

This study found that a novel thiohydantoin derivative, 3a, effectively inhibited androgen receptor activity in LNCaP cells and showed promising in vivo results by reducing testosterone-induced prostate changes, outperforming finasteride in mitigating prostate index and histopathological alterations.

This study synthesized new heterocyclic steroid derivatives and reported their promising antiproliferative activity against breast and prostate cancer cell lines, highlighting selectivity and impact on signaling pathways even in cells resistant to certain treatments.

This study found that tight junctions extend to the most superficial layer of the stratum granulosum in human skin, challenging previous claims of their limited presence in the epidermis.

This article explains that proliferating trichilemmal tumors, originating in the hair follicle, can exhibit low-grade malignant potential, and recommends wide excision to minimize recurrence risk, but reports no new clinical findings.

This study found that structural defects in the hair shafts of sighthounds with bald thigh syndrome are related to a downregulation of genes and proteins essential for hair shaft formation.

In this study, free flaps, specifically the ALT-free tissue transfer, were found to be safe and reliable for reconstructing large scalp defects requiring both scalp and skull repairs, with consistent results observed in clinical applications.

This study found that fractional CO(2) laser treatments led to significant improvements in eyelid skin tightening and eyebrow elevation over one year, with no significant side effects reported.

This study found that the ablation of Esrp1 and Esrp2 disrupts epithelial tight junctions by affecting Arhgef11 isoform expressions, highlighting a potential mechanistic link between splicing alterations and epithelial barrier defects.

This study found that treating reconstructed human epidermis with beta-lipohydroxy salicylic acid increased tight junction remnants in the stratum corneum, potentially affecting skin cohesion and desquamation.

This study confirmed the porcine ear skin model's effectiveness for studying nanoparticle-based drug delivery in human hair follicles, noting particle-dependent uptake and enhancement by massage.

This study found that overexpression of Claudin 6 in mice led to incomplete epidermal formation and hair abnormalities, suggesting its crucial role in skin differentiation and hair follicle development.

This study evaluated 23 cases of MRKH syndrome undergoing neo-vaginal reconstruction using islanded pudendal thigh flaps, finding a 100% flap survival and patency rate, along with satisfactory functional and aesthetic outcomes despite minor issues like hair growth in some patients.

The authors report a rare case of trichilemmal carcinoma in the thigh of a 71-year-old, emphasizing the importance of complete surgical excision to prevent recurrence and support patient prognosis.

This study found that stem cells can temporarily act as non-professional phagocytes during hair cycle regeneration by clearing apoptotic cells through a process requiring local lipids and retinoids for activation, providing insights into their dual role in maintaining tissue integrity.

This study found that males have significantly longer hair on their thighs compared to females, mainly due to a longer anagen phase and a greater rate of growth.

In this study, researchers observed that extract from Eclipta prostrata significantly stimulated hair growth and increased hair length in Wistar rats, which had inhibited hair growth induced by cyclophosphamide, compared to the control model.

In this study on Swiss albino mice, researchers reported that perilla leaf extract stimulated hair growth similarly to minoxidil, counteracting hair loss induced by testosterone injections.

Data-driven methods can help understand microbiota's role in diseases and develop personalized treatments.

In this study, researchers assessed the effects of a shampoo containing pomelo peel essential oil and Bồ Kết on hair growth in shaved white mice, finding it promoted faster, longer, and denser hair growth compared to untreated mice.

In this study, researchers examined skin growth and quality in Pekin ducks from 1 to 6 weeks of age, finding that skin factors like strength and collagen content increased with age and were influenced by gene expressions related to cell proliferation and collagen synthesis.

This review discusses the importance of early diagnosis and the management of hidradenitis suppurativa, reporting no new clinical results but highlighting current therapeutic approaches and need for collaboration in treatment.

In this study, a modified Ferriman-Galwey score greater than 4 was found to be effective for diagnosing hirsutism in Asian women, highlighting key areas such as the upper lip, thighs, and lower abdomen.

This study found that melanoma on the posterior scalp is associated with worse survival compared to other body sites, while sun-exposed areas showed better survival outcomes.