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A subtle androgen receptor abnormality can allow normal male development and sometimes fertility despite partial androgen resistance.

New 5% minoxidil foam effectively promotes hair growth and is safe for use.

Minoxidil breakdown varies by enzymes, affecting hair loss treatment effectiveness.

Minoxidil works in liver and outer hair root sheath for hair growth.

Using too much minoxidil foam can cause a rare movement disorder with facial twitching, but symptoms go away when the correct dose is used.

Minoxidil sulfate stimulates hair growth.

Minoxidil activates hair growth by being sulfated by P-PST in the human liver.

Hair follicle stem cells are a promising source for tissue repair and treating skin or hair diseases.

Minoxidil needs activation to work, and minoxidil sulfate helps with hair growth and blood pressure.

Men with male-pattern baldness have more androgen receptors in their scalp's oil glands, which may contribute to hair loss.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Dermatoscopy and videodermatoscopy are useful and reliable for tracking treatment progress in various skin conditions.

Human platelets change minoxidil to minoxidil sulfate, helping blood vessels widen.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Herbal nano-formulations show potential for effective skin delivery but need more research.

The document concludes that careful design of genetic fate mapping experiments is crucial for accurate cell lineage tracing in mice.

Scientists identified three genes important for processing certain brain chemicals, thyroid hormones, and medications.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Some domesticated animals have the same genetic skin diseases as humans, which can help doctors understand human genetic mutations.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

Scalp psoriasis treatments like strong corticosteroids and vitamin D3 analogues are effective, especially when combined.

Lower adrenal hormone levels may cause hair loss in postmenopausal women, certain patterns help diagnose nail cancer, and a gene variant linked to higher skin cancer risk in kidney transplant patients suggests monitoring folate levels.

Female relatives of PCOS patients have a higher chance of showing PCOS symptoms.

Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.

The MTHFR C677T mutation may increase the risk of alopecia areata in the Turkish population.

Minoxidil topical foam is a better, less irritating treatment for hair loss.

Minoxidil is processed in the body by an enzyme found in the liver and platelets.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

Heat stress changes goats' skin and hair at the microscopic level and affects their genes and skin bacteria.

Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.