July 2022 in “Journal of Investigative Dermatology” This study suggests that high platelet concentrations in PRP may not be necessary for hair growth in androgenetic alopecia, and certain growth factors might negatively impact clinical outcomes.
January 2024 in “The Journal of Dermatology” The authors concluded that a finasteride every other month regimen had similar maintenance effects to a daily regimen in men with androgenetic alopecia.
June 2025 in “Journal of Drug Delivery Science and Technology” A dissolving microneedle patch with dutasteride offers effective, long-lasting hair loss treatment with fewer side effects.
151 citations
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July 2011 in “Archives of Dermatological Research” This review discusses various strategies to enhance drug delivery through the skin barrier, highlighting liposomes as promising carriers for increased dermal concentrations in topical therapies, but reports no new research results.
June 2023 in “Clinica Chimica Acta” This study observed that both finasteride and dutasteride significantly decreased dihydrotestosterone concentrations in hair, with dutasteride showing the greatest reduction.
2 citations
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June 2024 in “Regenerative Therapy” In this study, ozone treatment was shown to increase the concentration of growth factors like EGF and TGF-β in PRP in vitro, suggesting that oxygen-rich PRP injections may provide an effective method for facial rejuvenation.
2 citations
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January 2023 in “BioMed Research International” The researchers reported that a 5% Beta vulgaris L. extract nanogel showed better antialopecic activity in testosterone-induced alopecia in mice compared to a 2.5% concentration.
1 citations
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August 2020 in “Journal of The American Academy of Dermatology” This letter discusses the variability in platelet-rich plasma preparation for androgenetic alopecia treatment and highlights that different methods yield varied platelet concentrations but not significant differences in growth factor secretion per platelet.
October 2025 in “Asian Journal of Pharmaceutical Research and Development” This study reported that phytosome formulations of citrus flavonoids naringenin and naringin showed significantly increased oral bioavailability and plasma drug concentration in rabbits, suggesting that phytosome technology effectively addresses the pharmacokinetic limitations of these compounds.
51 citations
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March 2019 in “Journal of cellular physiology” This review discusses the use of platelet lysate and its growth factors in treating diseases and regenerative medicine but reports no new clinical findings.
12 citations
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June 2010 in “Journal of dermatology” This study found that hyperpigmentation following contact immunotherapy for severe alopecia areata may indicate poor treatment responsiveness and aligns with characteristics of pigmented contact dermatitis.
3 citations
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January 1985 in “British Journal of Dermatology” In this study, a low concentration zinc sulphate solution was investigated for managing recurrent herpes simplex infections, but no new clinical results were reported.
April 2019 in “Journal of Investigative Dermatology” In this pilot study, combined platelet-rich plasma therapies showed potential benefits for improving skin elasticity and vascular network density in morphea patients, but the small sample size limits definitive conclusions.
54 citations
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January 2012 in “Vitamins & Trace Elements” This study found significantly lower serum vitamin D concentrations in patients with alopecia areata compared to healthy controls, suggesting that vitamin D deficiency may be a risk factor for this autoimmune hair loss disease.
33 citations
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April 1990 in “Dermatologic Clinics” Minoxidil effectively treats hair loss, with better results in women.
1 citations
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November 2025 in “Journal of Cosmetic Dermatology” This source reports on ongoing clinical trials examining the therapeutic potential of topical CBD for skin conditions like acne, dermatitis, and psoriasis, and emphasizes that upcoming trial results will be crucial in evaluating its effectiveness.
January 2024 in “Journal of Education, Health and Sport” This review discusses the modern production methods, mechanisms of action, and various uses of platelet-rich plasma in medicine, highlighting promising applications but noting the need for more high-quality research.
July 2024 in “Journal of Investigative Dermatology” PRP preparation partially activates platelets, causing varied growth factor release.
January 2023 in “Journal of orthopedics & bone disorders” This study suggests that platelet-rich plasma's high levels of growth factors may be limited in promoting bone regeneration due to the concurrent release of Dickkopf-1, which inhibits osteogenesis.
September 2020 in “Revista Digital de Postgrado” This review discusses the characteristics and dermatological applications of platelet-rich plasma and fibrin meshes and reports no new clinical results.
1 citations
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November 2024 in “Bone Reports” This study found that while MSC concentration in BMCs correlates with total cell counts, cellularity does not indicate high MSC content.
August 2023 in “Stem Cell Research & Therapy” This study found that cell-free fat extract (CEFFE) enhanced hair growth in mice with androgenetic alopecia by increasing hair follicle density and promoting proliferation while regulating the DHT/AR pathway.
April 2016 in “Journal of Investigative Dermatology” This study identified mefloquine as a potent inducer of lethal ER stress that effectively eliminated vemurafenib-resistant and sensitive melanoma cells, suggesting its potential for repurposing as a melanoma treatment.
13 citations
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July 2012 in “Dermatologic Surgery” Platelet-rich plasma (PRP) may help promote hair growth and improve graft survival after hair transplantation, but more research is needed to confirm its effectiveness and determine the best dosage.
December 2024 in “Jurnal Ilmiah Farmasi (Scientific Journal of Pharmacy)” This literature review reports that lavender essential oil exhibits various medicinal benefits, such as antibacterial and antioxidant properties, and that incorporating nanotechnology could enhance its effectiveness by improving solubility and stability.
15 citations
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June 2023 in “Molecules” This study focused on developing agarose/fucoidan hydrogels for the encapsulation of pancreatic cells, reporting that these materials supported cell viability and self-organization into pseudo-islets over 7 days, highlighting potential for diabetes treatment applications.
11 citations
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January 2016 in “Bipolar Disorder” This article reviews the uses, mechanisms, and side effects of valproate in treating bipolar disorder, noting its first-line status for several manic conditions but also highlighting serious risks such as fetal abnormalities.
April 2016 in “Plastic and reconstructive surgery. Global open” This article lists online educational resources from the American Society of Plastic Surgeons but reports no new research findings.
2 citations
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March 1964 in “Archives of Dermatology” This study found no significant difference in the therapeutic response to intralesional triamcinolone acetonide at concentrations of 2.5, 5, and 10 mg/mL for various dermatologic conditions.
September 2020 in “Medicina Moderna - Modern Medicine” This study found that a simple two-step method for preparing platelet-rich plasma produced satisfactory quality at a lower cost compared to many commercial systems, enabling smaller medical institutions to utilize PRP therapy.