research LFA-1 Blockade Prevents the Onset of Alopecia Areata in C3H/HeJ Mice
Blocking LFA-1 prevents hair loss in mice.
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150-180 / 716 resultsresearch Hair Follicle Immune Privilege and Its Collapse in Alopecia Areata
Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
research In Human Skin, UVB Initiates Early Induction of IL-10 Over IL-12 Preferentially in the Expanding Dermal Monocytic/Macrophagic Population
UVB exposure in human skin causes macrophages to produce more IL-10 and less IL-12, leading to immunosuppression.
research Targeting Integrin Pathways: Mechanisms and Advances in Therapy
New therapies are being developed that target integrin pathways to treat various diseases.
research Epigallocatechin-3 Gallate Inhibits STAT-1/JAK2/IRF-1/HLA-DR/HLA-B and Reduces CD8 NKG2D Lymphocytes in Alopecia Areata Patients
EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.
research Regulatory T Cells in Skin Regeneration and Wound Healing
Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.
research The JAK/STAT Signaling Pathway: From Bench to Clinic
The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.
research Hair Follicular Expression and Function of Group X Secreted Phospholipase A2 in Mouse Skin
sPLA2-X is crucial for normal hair growth and follicle health.
research Skin: Basic Structure and Function
The skin is a complex barrier that protects the body, regulates temperature, and helps with immune responses.
research Dyslipidemia in Patients with Androgenetic Alopecia: Statins, Finasteride, or Both?
Alopecia patients have higher heart disease risk; statins and finasteride may help.
research Prostaglandin D2 Inhibits Wound-Induced Hair Follicle Neogenesis Through the Receptor Gpr44
Prostaglandin D2 blocks new hair growth after skin injury through the Gpr44 receptor.
research Claudin-1 and Claudin-3 Maintain Proper Hair Follicle Structure and Regulate Telogen Effluvium
Claudin-1 and Claudin-3 are crucial for keeping hair follicle structure and preventing a type of hair loss called telogen effluvium.
research Aqueous Extract of Mentha Suaveolens Induces Nrf-2 Activation and Expression of Antioxidant and Detoxifying Enzymes in Human Keratinocyte HaCaT
Mint water extract boosts protective enzymes in skin cells.
research Orchestrated Cytotoxic and Skin Migratory Ability Lacking Self-Tolerance: Circulating γδT-Cells May Promote Alopecia Areata
The role of γδT-cells in causing alopecia areata remains unclear.
research Dissecting the Microenvironment Around Biosynthetic Scaffolds in Murine Skin Wound Healing
Different scaffold patterns improve wound healing and immune response in mouse skin, with aligned patterns being particularly effective.
research A Randomized Placebo-Controlled Single-Center Pilot Study of the Safety and Efficacy of Apremilast in Subjects with Moderate-to-Severe Alopecia Areata
Apremilast was not effective in treating moderate-to-severe alopecia areata.
research Significance of Iron Status in Hair Loss in Women
Iron deficiency might contribute to hair loss in women.
research Metabolic Syndrome and Skin Disease: Potential Connection and Risk
Some skin diseases may indicate a higher risk of metabolic syndrome and related health issues.
research Use of Contact Immunotherapy in the Treatment of Skin Diseases Other than Alopecia Areata
Contact immunotherapy might help treat various skin conditions, but more research is needed to confirm its safety and effectiveness.
research Teriflunomide and Its Mechanism of Action in Multiple Sclerosis
Teriflunomide helps reduce multiple sclerosis symptoms and is safe for most patients.
research Advanced Nanocarrier- and Microneedle-Based Transdermal Drug Delivery Strategies for Skin Diseases Treatment
Advanced nanocarrier and microneedle drug delivery methods are more effective, safer, and less invasive for treating skin diseases.
research Cutaneous and Mucosal Manifestations Associated with Celiac Disease
Celiac disease can cause skin problems that may get better with a gluten-free diet.
research Clinical and Histopathologic Features of Hair Loss in Patients with HIV-1 Infection
People with late-stage HIV-1 often experience a specific type of hair loss linked to multiple factors, including nutritional issues and immune responses.
research Tissue Resident and Follicular Treg Cell Differentiation Is Regulated by CRAC Channels
CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
research Enhanced Remyelination During Late Pregnancy: Involvement of the GABAergic System
Late pregnancy helps repair brain damage in rats due to the GABAergic system.
research MicroRNA in Skin Diseases
Certain microRNAs are linked to various skin diseases and could be used to diagnose and treat these conditions.
research Cutaneous Toxicities of New Treatments for Melanoma
New melanoma treatments can cause skin side effects, including skin cancer and rashes, but combining treatments may reduce these risks.
research Interferons in Dermatology
Interferons are effective for some skin conditions and cancers, but can have side effects and need more research for optimal use.
research Pathophysiology of the Burn Scar
Burn scars heal abnormally and more research is needed to find better treatments.
research Alopecia Universalis in an Adolescent Successfully Treated with Upadacitinib: A Case Report and Review of the Literature on the Use of JAK Inhibitors in Pediatric Alopecia Areata
A 14-year-old girl with severe hair loss regrew her hair using upadacitinib.