research Setipiprant for Androgenetic Alopecia in Males: Results from a Randomized, Double-Blind, Placebo-Controlled Phase 2a Trial
Setipiprant did not significantly improve hair growth in men with hair loss.
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research Structure Optimization of Tetrahydropyridoindole-Based Aldose Reductase Inhibitors Improved Their Efficacy and Selectivity
Optimizing the structure of a specific compound greatly improved its effectiveness and precision for treating diabetic complications.
research Biomarkers of Alopecia Areata Disease Activity and Response to Corticosteroid Treatment
Corticosteroid treatment reduces inflammation and alters hair keratins in alopecia areata.
research Toll-Like Receptor 3 Agonist, Polyinosinic-Polycytidylic Acid, Upregulates Carbonic Anhydrase II in Human Keratinocytes
A substance called poly(I:C) increases a protein called carbonic anhydrase II in skin cells, which might help with skin defense and healing.
research Somatostatin Expression in Human Hair Follicles and Its Potential Role in Immune Privilege
Somatostatin may help protect hair follicles from immune attacks.
research Prolactin and the Skin: A Dermatological Perspective on an Ancient Pleiotropic Peptide Hormone
Prolactin affects hair growth and skin conditions, and could be a target for new skin disease treatments.
research Pharmacotherapy for Keloids and Hypertrophic Scars
Combination pharmacotherapy is generally more effective for treating keloids and hypertrophic scars.
research Norepinephrine Regulates Keratinocyte Proliferation to Promote the Growth of Hair Follicles
Norepinephrine helps skin cells grow, which is important for hair growth.
research Hair Growth Inhibition by Psychoemotional Stress: A Mouse Model for Neural Mechanisms in Hair Growth Control
Stress can stop hair growth in mice, and treatments can reverse this effect.
research Dupilumab for the Treatment of Alopecia Areata in Children with Atopic Dermatitis
Dupilumab may help treat alopecia areata in children with atopic dermatitis, but it can also cause new hair loss.
research Improvement of Atopic Dermatitis and Alopecia Universalis with Dupilumab: A Case Report
Dupilumab can improve both atopic dermatitis and alopecia universalis.
research Both Lesional and Non-Lesional Skin from Acne Patients Shows Robust IL-17-Skewing and Upregulation of Antimicrobial Peptides
Acne patients' skin, both with and without lesions, shows a strong immune response and higher antimicrobial activity.
research Real-Life Experience with Belimumab in Systemic Lupus Erythematosus: Control of Disease Activity and Flares in a Multicenter Cohort
Belimumab effectively controls SLE disease activity and reduces steroid use.
research Th22 Is the Effector Cell of Thymosin β15-Induced Hair Regeneration in Mice
Th22 cells are essential for Tβ15-induced hair growth in mice.
research Clinical Application of Nonantibiotic Macrolides for Inflammation-Driven Immune Dysfunction in Inflammatory Skin Diseases
Nonantibiotic macrolides show promise for treating various inflammatory skin conditions.
research The Skin Mycobiome and Intermicrobial Interactions in the Cutaneous Niche
Certain fungi protect skin health, but changes can allow harmful fungi to cause serious infections, needing more research for treatment and control.
research Anticytokine Therapy, Particularly Anti-IFN-γ, in Th1-Mediated Autoimmune Diseases
Blocking interferon-gamma might help treat various autoimmune diseases.
research What's New in Dermatological Research?
2011 dermatological research found new skin aging markers, hair loss causes, skin defense mechanisms, and potential for new treatments.
research Endogenous Retinoids in the Pathogenesis of Alopecia Areata
Vitamin A affects hair loss and immune response in alopecia areata.
research Measurement of Serum Prolactin Level in Vitiligo Patients and Its Correlation with Prolactin Gene Polymorphism
Prolactin levels and gene polymorphism are not linked to vitiligo severity but are related to BMI.
research The Murine Hair Follicle Is a Melatonin Target
Melatonin directly affects mouse hair follicles and may influence hair growth.
research Highlights from the 68th Annual Meeting of the Society of Investigative Dermatology
The meeting discussed vitamin D3's role in fighting tuberculosis, potential treatments for skin conditions like psoriasis, and hair follicle regeneration as a possible solution for hair loss.
research Regulatory Roles of Androgens in Cutaneous Wound Healing
Testosterone may slow down wound healing and increase inflammation.
research Neurogenic Inflammation in Stress-Induced Termination of Murine Hair Growth Is Promoted by Nerve Growth Factor
Stress increases a factor in mice that leads to hair loss, and blocking this factor may prevent it.
research Tissue Resident Foxp3+ Regulatory T Cells: Sentinels and Saboteurs in Health and Disease
Foxp3+ Regulatory T Cells are important for immunity and tolerance, affect hair growth and wound healing, and their dysfunction can contribute to obesity-related diseases and other health issues.
research Cardiovascular Risk in Patients With Scarring and Nonscarring Alopecias: Assessing the Current State of Evidence
People with common hair loss conditions may have a higher risk of heart disease and related health issues.
research Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models
The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
research National Scientific Medical Meeting 1996 Abstracts
The document summarizes medical findings on topics like heart rhythm treatment, sleep apnea therapy, and various health conditions and treatments.
research Neuroimmunology of Stress: Skin Takes Center Stage
Stress can worsen skin and hair conditions by affecting the skin's immune response and hormone levels.
research Cutaneous Markers of Disorders Affecting Adult Horses
Skin and hair changes in horses can indicate serious diseases, and recognizing these signs is important for treatment and management.