research Keratin Is Not Only a Structural Protein in Hair: Keratin-Mediated Hair Growth
Keratin injections in mice can stimulate hair growth and might help treat hair loss.
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research Age-Dependent Loss of the Stemness and Antimicrobial Defense Function of Dermal Fibroblasts Is Mediated by TGFbeta
Aging reduces skin cell renewal and defense against germs due to TGFbeta, but blocking TGFbeta could help restore these functions.
research BJD Snippet
Researchers found certain genes are overactive and others are underactive in men with early balding, which could help create new treatments.
research Editor's Choice: November 2017 British Journal of Dermatology Highlights
Organ transplant recipients have a higher risk of skin cancer over time, atopic dermatitis skin shows unusual bacterial and fungal patterns, a new tool for measuring hidradenitis suppurativa severity was created, and gene expression changes in male baldness suggest new treatments.
research Editors' Picks
Activin increases skin tumor formation, skin Tregs help hair growth, lymph-node removal doesn't improve melanoma survival, cells can revert to stem cells in wound healing, and skin bacteria produce peptides that may treat infections.
research Efficacy of Asymmetric siRNA Targeting Androgen Receptors for the Treatment of Androgenetic Alopecia
cp-asiAR may effectively treat androgenetic alopecia by promoting hair growth and reducing androgen receptor activity.
research Regulatory Pathways Implicated in Male Androgenetic Alopecia Pathogenesis
Genes controlling hair growth and immune response are disrupted in male pattern baldness.
research Effects of Parthenolide on Androgenetic Alopecia in Mice and Human Follicle Dermal Papilla Cells
Parthenolide promotes hair growth in mice and may influence pathways related to male pattern baldness.
research Microneedling and Platelet-Rich Plasma: A 2018 Study on Effectiveness for Skin and Hair Conditions
Combining microneedling with platelet-rich plasma enhances skin repair and collagen production but may not offer significant extra benefits.
research Hair Growth Control by Follistatin
Follistatin is important for hair growth and could help treat hair loss.
research Fibromodulin Reduces Scar Formation in Adult Cutaneous Wounds by Eliciting a Fetal-Like Phenotype
Fibromodulin treatment helps reduce scarring and improves wound healing by making it more like fetal healing.
research Male Androgenetic Alopecia
Male pattern baldness involves hormone-related hair thinning, shorter hair, and inflammation.
research Wnt Signaling Activation: Targets and Therapeutic Opportunities for Stem Cell Therapy and Regenerative Medicine
Wnt activation shows promise for regenerative medicine but requires selective targeting to minimize risks like cancer.
research The Effect of Lactobacillus Plantarum Hydrolysates Promoting VEGF Production on Vascular and Hair Growth in C57BL/6 Mice
Lactobacillus plantarum hydrolysates may help increase hair growth by boosting VEGF production.
research Microneedling in Dermatology: A Review
Microneedling is effective for skin rejuvenation and various skin issues, but more research is needed to confirm its safety and effectiveness.
research The Biodisposition and Hypertrichotic Effects of Bimatoprost in Mouse Skin
Bimatoprost increases hair growth in mice without breaking down into other substances.
research Anti-Mullerian Hormone: A Potential Marker for Recruited Non-Growing Follicles of Ovarian Pool in Women with Polycystic Ovarian Syndrome
AMH levels are higher in women with PCOS and can indicate the number of small follicles in their ovaries.
research Canonical and Non-Canonical Wnt Signaling Control the Regeneration of Amputated Rodent Vibrissae Follicles
Both main and alternative Wnt signaling are important for regrowing rodent whisker follicles.
research New Drug Targets and Research Methods for Androgenetic Alopecia
The document concludes that more research is needed to create specific drugs for treating male pattern baldness.
research Oral Cyclosporin Does Not Arrest Progression of Androgenetic Alopecia
Oral cyclosporin doesn't stop hair loss.
research Autologous Platelet-Rich Plasma Injection Therapy
PRP injection therapy shows promise for treating hair loss, increasing hair count and thickness with minimal side effects.
research The Circadian Molecular Clock Creates Epidermal Stem Cell Heterogeneity
The circadian clock affects skin stem cell behavior, impacting aging and cancer risk.
research Molecular Control of Epithelial-Mesenchymal Interactions During Hair Follicle Cycling
Epithelial-mesenchymal interactions control hair growth cycles through specific molecular signals.
research Autologous Platelet-Rich Plasma: A Potential Therapeutic Tool for Promoting Hair Growth
Platelet-rich plasma can potentially promote hair growth by stimulating cell growth and increasing certain proteins.
research Overexpression of Activin A in the Skin of Transgenic Mice Reveals New Activities in Epidermal Morphogenesis, Dermal Fibrosis, and Wound Repair
Overexpression of activin A in mice skin causes skin thickening, fibrosis, and improved wound healing.
research Cutaneous Signs in COVID-19 Patients: A Review
COVID-19 can cause different skin symptoms that may help with early diagnosis and show how severe the disease is.
research Dihydrotestosterone-Inducible Dickkopf 1 from Balding Dermal Papilla Cells Causes Apoptosis in Follicular Keratinocytes
A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.
research Enhanced Effect of Platelet-Rich Plasma Containing a New Carrier on Hair Growth
Platelet-rich plasma with a new carrier significantly increases hair thickness without serious side effects.
research Hairless Triggers Reactivation of Hair Growth by Promoting Wnt Signaling
The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
research Tregs: Where We Are and What Comes Next?
The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.