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Using polymeric micelles to deliver spironolactone topically could improve wound healing in skin affected by glucocorticoids.

Testosterone replacement may improve sexual desire and bone health in women with low androgen levels, but more research is needed on its long-term safety.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Young women with diffuse hair loss may have low SHBG levels, which could lead to more active testosterone and contribute to their hair loss.

Testosterone replacement may help postmenopausal women with sexual function and bone density, but suitable treatments are limited.

The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Nandrolone and oxandrolone could help treat male health issues like muscle loss and low testosterone.

Liquorice may reduce testosterone and affect male reproductive organs, potentially helping treat conditions like prostate cancer.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Testosterone therapy for transmasculine individuals is generally safe with medical supervision, improves mental health, and has mixed effects on physical health.

Cocaine impairs male sexual behavior and alters testosterone metabolism in the brain.

Testosterone, progesterone, and levonorgestrel change enzyme levels related to fat production in hamster skin, which could affect skin oil and acne.

AGA causes hair loss by shrinking hair follicles due to DHT binding, and can be treated with finasteride and minoxidil.

Mesenchymal stem cells show potential for skin healing and anti-aging, but more research is needed for safe use, especially regarding stem cells from induced pluripotent sources.

Men with moderate hair loss had the best spatial thinking, and long-term DHT might affect cognition.

Androgens, like DHT, affect hair growth and treatments like finasteride may help.

Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.

Eccrine sweat gland's clear cells likely cause excessive sweating in hyperhidrosis.

Hesperidin helps protect against testicular damage caused by finasteride.

Coffee and tea might help hair growth in balding individuals, but side effects and alternative uses are being considered.

Formononetin, found in red clover, may treat hair loss with fewer side effects.

Finasteride and flutamide effectively reduce hirsutism in PCOS women, with flutamide also lowering hormone levels.

New treatments for hair loss are being developed using molecular biology.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Finasteride in male rats causes liver and metabolic issues in their offspring.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Finasteride exposure in pregnancy causes genital abnormalities in male rats.

The conclusion is that the best initial treatment for hirsutism is usually oral contraceptives, with the addition of antiandrogens or insulin sensitizers if needed, and topical eflornithine or laser treatments as supplementary options.