August 2024 in “Journal of Cosmetic Dermatology” CGF injections may safely and effectively promote hair growth in androgenetic alopecia patients.
July 2021 in “IntechOpen eBooks” Ginseng, especially its component ginsenosides, can promote hair growth, reduce hair loss, and potentially treat conditions like alopecia by affecting cell pathways and cytokines.
3 citations,
December 2022 in “Nutrients” Limonin from young citrus fruits may help with hair growth by affecting cell growth and hair cycle pathways.
November 2024 in “Plants” Et-BB3-CMU rice bran extract may be a promising natural option for promoting hair growth and preventing hair loss.
14 citations,
November 1982 in “British Journal of Dermatology” Testosterone conversion to 5α-DHT may not be essential for its effects on the skin.
45 citations,
May 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.
12 citations,
October 2018 in “Aging male/The aging male” Higher BMI and lower testosterone are linked to more aggressive prostate cancer.
1 citations,
January 2020 in “Egyptian Journal of Dermatology and Venereology” Higher testosterone and DHT levels are linked to hair loss in men, but not to prostate cancer risk.
28 citations,
November 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The normal human prostate does not significantly affect blood DHT levels.
11 citations,
November 1982 in “British journal of dermatology/British journal of dermatology, Supplement” Testosterone and some of its forms can strongly stimulate oil gland growth in skin.
8 citations,
March 2012 in “The Journal of Steroid Biochemistry and Molecular Biology” Testosterone and dihydrotestosterone have similar effects on body composition and metabolic health in men.
8 citations,
May 1982 in “Journal of Endocrinology/Journal of endocrinology” Rat skin takes up and processes testosterone differently than other organs, with testosterone being more important for the skin than its metabolite 5α-DHT.
January 2024 in “Journal of Medicinal Food” Rambutan extract can help reverse hair loss caused by testosterone.
2 citations,
January 2011 in “Springer eBooks” Finasteride is a medicine used to treat enlarged prostate and prostate cancer, and it works by changing how testosterone works in the body.
January 2018 in “Elsevier eBooks” 5α-reductase-2 deficiency causes ambiguous genitalia at birth and affects male sexual development, but individuals often develop male characteristics at puberty.
17 citations,
July 2003 in “Metabolism-clinical and Experimental” Women with female-pattern baldness produce more testosterone, but 5a-reductase inhibition treatment won't help.
14 citations,
February 2018 in “Psychoneuroendocrinology” Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
10 citations,
October 2012 in “Andrology” Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
7 citations,
July 1995 in “PubMed” Finasteride, a drug that changes testosterone to a different hormone, was studied and its effects over time were modeled successfully.
1 citations,
June 2021 in “Singapore Medical Journal” Dutasteride and finasteride can help increase hair growth gene expression but need further improvement.
May 2024 in “Current perspectives on medicinal and aromatic plants” Plant-based treatments might help with hair loss and have fewer side effects than synthetic drugs.
October 2022 in “Endocrine journal” Testosterone and dihydrotestosterone treatments can help with penile growth in males with 5α-reductase type 2 deficiency, with dihydrotestosterone being more effective in infancy.
April 2022 in “Diabetes Therapy” Low testosterone does not prevent prostate cancer in men with type 1 diabetes.
5 citations,
May 2012 in “Andrologia” Finasteride use may be linked to rare testicular tumor, but more research needed.
70 citations,
April 2014 in “Annales d'endocrinologie” New genes and pathways are important for testosterone production and male sexual development.
19 citations,
March 1998 in “Endocrinology” Male rats have more somatostatin neurons than females due to testosterone converting to estrogen during early development.
59 citations,
May 2014 in “Expert Opinion on Therapeutic Targets” The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
11 citations,
January 2000 in “The Journal of Steroid Biochemistry and Molecular Biology” LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.
4 citations,
December 2014 in “PubMed” Pre-operative hormone treatment for hypospadias surgery might improve outcomes, but more research is needed to confirm.
19 citations,
April 2014 in “Hormones” Hormones and genetics play key roles in male and female baldness, which can affect mental health and may be linked to other health issues.