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This study suggests that berberine may offer multiple benefits for women with polycystic ovary syndrome by improving metabolic and hormonal profiles, though further research is needed on its long-term effects on reproductive outcomes.

This study observed that women with PCOS exhibited higher levels of triglycerides, fasting insulin, HOMA-IR, total testosterone, DHEAS, and LH/FSH ratio, and lower HDL cholesterol compared to healthy controls, with these markers varying across different PCOS phenotypes.

In this study using rat hippocampal cultures, progesterone and testosterone showed neuroprotective effects against oxygen-glucose deprivation-induced neuronal cell death, while metabolism of these hormones in the brain may affect their protective actions.

Equol may help with antiaging and skin health by boosting collagen and blocking certain hormones.

This study suggests that adding metformin to diet and exercise improves insulin resistance and hyperandrogenism in women with PCOS, though lifestyle changes alone may enhance menstrual cycles.

This study found that N-acetylcysteine was as effective as metformin in improving insulin resistance and metabolic syndrome parameters in women with polycystic ovary syndrome, with fewer side effects.

In this randomized controlled trial, combining cinnamon and inositol led to significant improvements in metabolic and hormonal parameters, such as reduced LH, testosterone, fasting glucose, and ovarian ultrasound scores, in overweight women with PCOS, indicating superior benefits over either supplement alone.

In this study, PCOS patients had lower Spexin levels, which were inversely associated with adverse metabolic and hormonal profiles, suggesting a role for Spexin in PCOS pathways.

In this study, selective overexpression of androgen receptors in muscle cells increased lean muscle mass and reduced fat mass in transgenic rodents, suggesting a potential target for drug development.

This study found that among women with polycystic ovary syndrome, higher levels of the hormones estrone and free testosterone were associated with an increased cardiometabolic risk, especially in those who were overweight or obese.

This study reported that both drospirenone and chlormadinone acetate oral contraceptives had similar beneficial effects on clinical, metabolic, and hormonal parameters in women with polycystic ovary syndrome over six months.

This review evaluates the hormonal, metabolic, and clinical aspects of a male equivalent PCOS syndrome in men and highlights areas where further research is needed, reporting no new empirical findings.

This study found that adolescents with androgenetic alopecia showed distinct hormonal profiles between boys and girls, with concurrent metabolic dysfunction present in both sexes, highlighting the need for sex-specific diagnosis and management approaches.

This case presentation highlights a 26-year-old woman with PCOS, metabolic syndrome, and prediabetes, emphasizing the importance of early recognition and multidisciplinary management to prevent long-term metabolic complications.

This case study details a 26-year-old woman diagnosed with PCOS and metabolic syndrome, highlighting the importance of early recognition and multidisciplinary management to improve reproductive and metabolic health outcomes.

In this study, an Egyptian cohort with PCOS showed a high prevalence of skin issues like hirsutism and acne compared to controls, with hirsutism linked to higher androgen levels, while other factors also influenced acne and alopecia.

This study concluded that steroid deficiencies were significantly more severe in men with panhypopituitarism than in those with isolated gonadotropin deficiency.

This study found that PCOS is common among Iranian women, with phenotypes involving hyperandrogenism exhibiting worse lipid profiles and higher rates of metabolic syndrome compared to healthy women.

This study found that hypothyroidism in women with PCOS significantly increased insulin resistance and obesity, which might worsen metabolic issues and impact conditions like hair loss and infertility.

This study found that an 8-week low insulinemic diet significantly improved anthropometric, biochemical, and metabolic measures, binge eating behaviors, and quality of life in women with PCOS.

This study found that anovulatory PCOS patients were younger, had longer menstrual cycles, and higher systolic blood pressures compared to ovulatory patients.

In this study, researchers found that hirsutism in Egyptian women with PCOS was associated with higher testosterone levels, while acne and androgenetic alopecia did not correlate with androgen levels or insulin resistance.

In this study, hirsutism in women with PCOS was strongly associated with hyperandrogenism and metabolic abnormalities, while acne and androgenic alopecia were not effective markers for hyperandrogenism.

Metformin improves menstrual cycles and hormone levels in women with PCOS, mostly within the first 6 months.

This study found that spinach-derived thylakoid supplementation, combined with a calorie-restricted diet, led to more significant improvements in weight loss and insulin sensitivity in obese women with PCOS than calorie restriction alone.

This study found that the Keyora Lycopene 23 in 1 formulation may improve various aspects of male endocrine and reproductive health by targeting oxidative stress, nitric oxide deficiency, and hormonal imbalance.

In this study, the researchers introduced the Keyora Lycopene 23 in 1 formulation, demonstrating its potential to improve male endocrine and reproductive health by addressing oxidative stress, nitric oxide deficiency, androgen imbalance, and mitochondrial dysfunction through a comprehensive multi-nutrient approach.

Acne and hair loss are not good indicators of hormone imbalance in PCOS, but excessive body hair is.

This study found that men with androgenic alopecia had significantly higher levels of certain urinary steroid metabolites, suggesting increased 5 alpha-reductase activity and possible mild hyperadrenal activity.

This review discusses the role of androgen therapy and neurosteroids in cerebrovascular health, highlighting the potential risks and benefits and the importance of pharmacogenetic testing, but reports no new experimental results.