TLDR Women with PCOS have higher cardiometabolic risks.
This study investigated the cardiovascular and metabolic risk profiles of 240 women with polycystic ovary syndrome (PCOS) compared to 116 healthy controls. The women with PCOS were divided into four phenotypes based on the presence of hyperandrogenism, oligo/anovulation, and polycystic ovaries. The results showed that women with PCOS had significantly higher levels of triglycerides, fasting insulin, HOMA-IR, total testosterone, DHEAS, and LH/FSH ratio, and lower HDL cholesterol compared to controls. These findings highlight the increased cardiometabolic risks associated with PCOS, emphasizing the need for phenotype-specific management strategies.
3 citations
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September 2025 in “Frontiers in Cardiovascular Medicine” 70 citations
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February 2025 in “Journal of Ovarian Research” 
2 citations
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July 2023 in “Frontiers in Endocrinology” The review found that current care models for PCOS are not fully effective and more research is needed, especially in low-income countries.
18 citations
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July 2019 in “Clinical Endocrinology” Women with PCOS in Sicily show different levels of metabolic problems depending on their PCOS type, with obesity and abnormal lipid profiles being common.
145 citations
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March 2010 in “Fertility and Sterility” Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.
286 citations
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January 2009 in “Human Reproduction Update” Women with the NIH type of PCOS have more obesity and higher risk of diabetes and heart disease than those with other types of PCOS.
166 citations
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March 2007 in “Hypertension” High androgen levels in young women with PCOS are linked to higher blood pressure.
947 citations
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February 2004 in “The Journal of Clinical Endocrinology and Metabolism” Most women with excess male hormones have Polycystic Ovary Syndrome, and hormonal therapy can improve symptoms but may cause side effects.
58 citations
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November 2020 in “International Journal of Molecular Sciences” SHBG may be a useful early indicator and treatment target for PCOS.
257 citations
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July 2018 in “Obstetrics & Gynecology” PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.
343 citations
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October 2015 in “Endocrine Practice” The guide recommends specific methods for diagnosing PCOS and various treatments for its symptoms, while considering the health impacts on adolescents.
October 2023 in “International Journal For Multidisciplinary Research” Women with PCOS face many health risks, but exercise, a healthy diet, and weight management can help.
1 citations
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August 2023 in “Diagnostics” Women with PCOS are more likely to develop kidney stones, especially those with certain PCOS types.
53 citations
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September 2014 in “Reproductive Biology and Endocrinology” Different types of PCOS have different levels of metabolic problems, with the most severe type showing the highest disturbances.
