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Cyclosporine A therapy changes sex hormone levels differently in pre-menopausal and post-menopausal women with primary biliary cirrhosis.

People with lower levels of free testosterone tend to have worse COVID-19 outcomes.

The conclusion is that managing androgen excess requires long-term treatment, including hormonal contraceptives and androgen blockers, with follow-up after six months.

S5αR inhibitors might help treat schizophrenia and other mental disorders but need more research.

5α-reductase inhibitors help treat disorders caused by DHT and have potential for future therapies.

Melatonin may help treat PCOS symptoms in rats.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Four-amino acid part makes enzyme sensitive to finasteride.

Men with Type 2 Diabetes have lower DHT levels, which may affect fertility and lipid profiles.

Antiandrogens, particularly flutamide and CPA, are most effective for treating hirsutism, with long-term use needed for best results.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Some skin diseases and their treatments can negatively affect male fertility.

CBG may help with various medical conditions but needs more human research to confirm safety and effectiveness.

Finasteride affects brain processes related to neurotransmission and metabolism, potentially helping with neuropsychiatric conditions.

Isotretinoin improves severe acne without changing androgen or insulin levels but may increase body weight and triglycerides.

CB-03-01 is a promising skin cream for treating hormone-related skin problems without causing harmful body-wide effects.

Anti-acne medications may work by reducing the activity of a protein involved in acne development.

Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Acne is a common skin condition linked to diet, hormones, and genetics, and early treatment can prevent scarring.

Finasteride may lower cholesterol and slow heart disease progression.

Steroid Sulfatase inhibitors show promise in treating hormone-dependent disorders like cancers, hair loss, and acne, with 667COUMATE being a potential candidate for breast cancer treatment trials.

Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.

The document suggests creating a validated score to diagnose Cushing's Syndrome and considers plasma steroid profiling as a simpler diagnostic method.

We now understand more about what causes acne and this could lead to better, more personalized treatments.

Analyzing bear poop helps measure their stress without harming them.

The study found that the hair loss condition in Cesky Fousek dogs is influenced by multiple genes affecting skin and muscle structure, fat metabolism, and immunity.

A group has developed therapies that show promise for treating cancer and various other conditions.

Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.