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Finasteride negatively affects fish reproduction and gonadal development.

Fadrozole and Finasteride change frog sex ratios and cause intersex animals with altered gene expressions.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Father's finasteride use may affect son's fertility and testicular function.

Infertile men are more likely to produce sperm with abnormal chromosome numbers, which can affect pregnancy success and embryo health.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Finasteride exposure harms tadpole reproduction and hormone balance.

COVID-19 may harm male fertility and damage the reproductive system.

COVID-19 may affect male fertility and women might have better outcomes due to hormonal and immune differences.

The document concludes that accurate diagnosis of male and female gonadal disorders is crucial for effective treatment and better patient outcomes.

Testosterone replacement therapy can prevent men from fathering children and should not be used by those wanting to stay fertile.

Thyroid hormones and androgens affect gene expression in frog reproductive organs differently between males and females.

Androgen self-administration might be controlled by membrane receptors, not nuclear ones.

More research is needed to understand how testosterone is maintained in adult males.

The document concludes that early diagnosis and treatment of Congenital Adrenal Hyperplasia are crucial for preventing serious health issues and improving patient outcomes.

Finasteride reduces male rat fertility by causing issues with copulatory plug formation.

Amenorrhea is when a woman doesn't have periods, with primary amenorrhea starting by age 15 or within five years of breast development, and secondary amenorrhea when periods stop for three months. It affects 3-4% of women not pregnant, breastfeeding, or in menopause, mainly due to polycystic ovary syndrome, hypothalamic amenorrhea, hyperprolactinemia, and ovarian failure.

Amenorrhea, or the absence of periods, should be evaluated by age 15 or within five years of early breast development, and is most commonly caused by conditions like polycystic ovary syndrome and hypothalamic amenorrhea.

The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.

Finasteride blocks progesterone production in specific tumor cells, potentially causing side effects.

The document concludes that sex hormones are crucial for mammalian reproduction, health, and behavior, and require more research for therapeutic use.

Genetic mutations can affect female sexual development, requiring personalized medical care.

Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Male hormones may play a role in the development of heart disease, and more research is needed to understand their effects.

Human skin can make serotonin and melatonin, which help protect and maintain it.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Surgeons must understand the full care process for gender confirmation surgery to help transgender individuals effectively.

Amenorrhea is relatively rare and initial testing should check FSH, TSH, and prolactin levels.