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Sulforaphane from broccoli may help treat certain cancers, hormone issues, and hair loss.

Male pattern baldness is linked to higher levels of a certain receptor in the scalp, which leads to the shrinking of blood vessels and hair loss. Early treatment targeting this receptor could be more effective.

Cross-sex hormone therapy is important for managing gender dysphoria and requires careful monitoring and healthcare provider education.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

Some drugs may reduce prostatitis symptoms short-term with few side effects.

Finasteride may affect PNMT, causing side effects.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.

Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Lack or blocking of SRD5a, a key component in hormone creation, can lead to conditions like pseudohermaphrodism and affect hair growth, bone mass, muscle strength, and reproductive health. More research is needed on its regulation from fertilization to adulthood.

Different sPLA2 enzymes affect immunity, skin and hair health, reproduction, and may be potential targets for therapy.

The review highlights the need for more research on transgender dermatology, the role of dermatologists in gender affirmation, and the effects of hormone therapy on skin and hair.

Finasteride treats enlarged prostate, improves urinary flow, but may cause sexual side effects.

Acne can appear or persist in adulthood due to hormonal changes, external factors, or substance use, and requires appropriate treatment.

The safety and effectiveness of gender-affirming treatments for children are uncertain, with potential long-term risks like infertility.

Hormone therapy for transgender females increases the risk of blood clots and requires careful dosing, monitoring, and lifelong management.

Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Kolaviron and quercetin may help treat prostate issues.

Most legal cases about 5α-reductase inhibitors, drugs for hair loss and prostate issues, complain about side effects and delayed cancer diagnosis, with most lawsuits settled out of court.

Oestrogens help maintain healthy skin, heal wounds, and may protect against skin aging and cancer.

Zinc is crucial for growth and health in rats.

Finasteride for hair loss may cause persistent sexual symptoms, depression, anxiety, and lower quality of life.

Finasteride for hair loss increases risk of long-lasting sexual dysfunction.

The conclusion is that future hair loss treatments should target the root causes of hair thinning, not just promote hair growth.

The guideline recommends mental health involvement in diagnosing gender identity disorder and outlines hormone and surgical treatment protocols, emphasizing safety, informed consent, and long-term monitoring.

Antiandrogens and androgen inhibitors like spironolactone, finasteride, and dutasteride can treat hair loss and skin conditions, but they have risks and side effects, including potential harm to pregnant women and risks of cancer and heart issues. Herbal remedies also have antiandrogenic effects but lack safety validation.

Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.

Finasteride causes lasting fertility decrease in rats.