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Hydroxychloroquine showed some potential, but overall, the three drugs had limited success in treating lupus in dogs.

Finasteride causes lasting fertility decrease in rats.

Aldactone was more effective in reducing hair growth in women with hirsutism than Diane, despite having less impact on hormone levels.

Hair growth is influenced by factors like genetics and nutrition, and more research is needed to understand hair loss and growth mechanisms.

Finasteride for hair loss increases risk of long-lasting sexual dysfunction.

People undergoing chemotherapy need better support and information to cope with hair loss.

Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.

Melatonin-loaded nanocarriers improve melatonin delivery and effectiveness for various medical treatments.

The document concludes that non-operative treatment for gender dysphoria is safe and effective, and hormone therapy does not increase cancer risk.

The L457(3.43)R mutation in the human lutropin receptor causes increased activity and hormone insensitivity, leading to precocious puberty.

The new FDA labeling rules provide more detailed drug safety information for pregnant and breastfeeding women, but more data is needed on the risks of many dermatologic drugs.

Finasteride may cause lasting sexual, mental, and physical symptoms; use with caution.

Various treatments, including FDA-approved drugs, natural products, and oral supplements, can help with hair loss, but a patient's medical history and potential allergies should be considered when choosing a treatment.

PFS might be a delusional disorder with potential to become mass psychogenic illness.

The document concludes that hormonal biomarkers are key for diagnosing hyperandrogenemia in women and hypogonadism in men.

Women with congenital adrenal hyperplasia have lower fertility, but with proper treatment, they can conceive successfully.

Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.

Finasteride affects young male rats' brain function and behavior negatively.

Healthcare providers need better understanding and cultural sensitivity to improve care for transgender patients with kidney failure needing transplants.

Stem cells compete for space using cell adhesion, and mutations can affect their competitive success, with implications for tissue health and disease.

Changes in testosterone and estrogen receptor genes can affect how men age, influencing body fat, hair patterns, and possibly leading to skin disorders.

Combination therapies work better than single treatments for hair loss.

Some men taking finasteride for hair loss may experience sexual problems like erectile dysfunction and decreased sex drive, which can persist even after stopping the medication.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

Zinc is important for growth and health in animals, plants, and humans, and not having enough can cause various problems.