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LY320236 is a strong blocker of two enzymes that change testosterone into dihydrotestosterone and might help treat conditions related to male hormones.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

TURP is the best treatment for BPH, but some patients prefer medications like alpha-blockers and finasteride.

5α-reductase inhibitors like finasteride may not be effective or safe for transgender individuals, and more research is needed.

Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.

Men using hair loss drugs like finasteride may experience sexual side effects like erectile dysfunction, but it's unclear who will be affected and when. Treating depression and sexual symptoms is suggested, as these men often have higher rates of both. More research is needed to understand why these side effects occur.

Healthcare providers need better education and resources to give competent and sensitive care to transgender patients.

A woman's masculine symptoms were caused by an ovarian tumor, which improved after surgery.

The document concludes that hormone therapy is essential for treating gender dysphoria, with specific drugs and monitoring protocols recommended for safety and effectiveness.

Finasteride changes antioxidant enzyme expression, possibly affecting sperm protection in rats.

A combination of nanomilled oral testosterone and dutasteride normalized testosterone levels in men with low testosterone and is safe for short-term use.

Storing hair follicles in special buffers with added protective substances can increase hair growth and reduce cell death.

New drugs targeting DNA enzymes show promise for cancer treatment but have side effects like immune system suppression and hair loss.

Finasteride use can cause lasting negative effects like sexual dysfunction, depression, anxiety, and cognitive issues.

The study concluded that both estrogen and androgen receptors, which decrease with age, are linked to skin aging and may be hormonally regulated.

Certain genetic variants in the androgen receptor are linked to higher PSA levels, potentially affecting prostate cancer screening outcomes.

Certain gene variations are linked to better memory in healthy Chinese women.

Blocking interferon-gamma might help treat various autoimmune diseases.

Topical minoxidil is the most promising treatment for male pattern hair loss, but more research is needed to confirm its effectiveness and safety.

Finasteride treatment changes urine metabolomics and steroid signatures, potentially monitoring effectiveness but may cause sexual side effects.

Finasteride and minoxidil together safely and effectively increase hair growth and density for androgenetic alopecia.

Smaller finasteride particles increase effectiveness in treating hair loss.

Finasteride use may increase the risk of male breast cancer.

D-004 may be a natural alternative to finasteride for treating enlarged prostate and male baldness.

Proscar (finasteride) blocks 5α-reductase in sea urchin ovaries and testes, suggesting potential treatment for androgen-related conditions.

Certain adrenal hormones can strongly stimulate oil gland growth in hamster skin, similar to male hormones.

Cyproterone acetate is the preferred treatment for women's hyperandrogenism when estrogen/progestogen use is safe.

Cytochrome P-450 enzymes in the skin help break down various substances and could be targeted to treat skin conditions.

Flutamide, an antiandrogen, has minimal impact on female rat endocrine systems and does not significantly change their reproductive cycles.

Men with liver cancer have higher levels of a specific testosterone byproduct in their liver and blood, despite overall lower male hormone levels.