19 citations
,
April 2015 in “Stem Cells” This study demonstrated that supplementing aged mice with pro-IGF-II improved muscle regeneration by enhancing satellite cell proliferation and reducing adipogenesis, suggesting potential benefits for treating muscle injuries in elderly individuals.
16 citations
,
July 2012 in “The New England Journal of Medicine” This case report describes a 27-year-old man hospitalized with fatigue, myalgias, weakness, profound weight loss, and abnormal liver function, leading to a diagnosis after chest imaging revealed pneumomediastinum.
16 citations
,
December 2004 in “Aesthetic surgery journal” This review discusses a multistage hand rejuvenation protocol involving topical therapies, intense pulsed light, autologous fat injections, and surgical excision, but reports no new clinical results.
14 citations
,
November 2020 in “International Journal of Molecular Sciences” This review article summarizes the potential role of advanced medical therapies—using genes, cells, and/or tissue engineering—in treating various types of alopecia, by examining clinical research, basic studies, and ongoing trials.
13 citations
,
November 2024 in “Frontiers in Microbiology” This review assessed the potential of mesenchymal stem cell therapy to enhance burn wound healing, highlighting its capabilities in promoting angiogenesis, reducing inflammation, and regenerating damaged tissues, while identifying preclinical and clinical challenges that need addressing to optimize treatment outcomes.
13 citations
,
February 2017 in “Science” Turning scar-forming cells into fat cells can reduce scarring.
12 citations
,
April 2025 in “Discover Pharmaceutical Sciences” This review examines microneedle patches for drug delivery, detailing their designs, materials, manufacturing methods, and potential advantages, but reports no new clinical results.
12 citations
,
December 2020 in “Frontiers in Cell and Developmental Biology” This review covers the variability in methods for preparing platelet-rich plasma and reports no new clinical results, suggesting that this variability may contribute to inconsistent efficacy in clinical trials.
12 citations
,
March 2018 in “Bioengineering” This review discusses the use of non-transfusional hemocomponents in surgical procedures for tissue regeneration and reports no new empirical findings.
12 citations
,
April 2015 in “InTech eBooks” Platelet Rich Plasma (PRP) shows promise for tissue repair and immune response, but more research is needed to fully understand it and optimize its use.
11 citations
,
March 2024 in “Cell and Tissue Research” In this review, researchers summarize the methods for characterizing telocytes, outline their physiological roles and implications in diseases, and discuss potential future studies including precise markers and targeted therapies.
11 citations
,
March 2016 in “Translational Andrology and Urology” This review highlights the potential therapeutic applications of nandrolone, an anabolic steroid, for male health, but notes that more human studies are needed due to limited existing literature.
10 citations
,
November 2024 in “Nature Reviews Cardiology” Skin conditions can signal heart issues, highlighting the need for integrated care.
10 citations
,
April 2018 in “Facial Plastic Surgery” This article reviews scalp advancement and forehead shortening when combined with a brow lift, focusing on reducing temporal recession, but reports no new clinical results.
10 citations
,
January 2016 in “Global Dermatology” This study observed that zinc deficiency in humans and mice was associated with diminished allergic contact dermatitis but increased severity and duration of irritant contact dermatitis.
9 citations
,
May 2024 in “Cureus” This review discusses the role of platelet-rich plasma in assisted reproductive technology for enhancing endometrial receptivity and reports promising outcomes.
9 citations
,
November 2018 in “Drug Discovery Today” This review discusses insights from scar-free animal models and cellular factors in skin regeneration, suggesting potential strategies for developing scar-free treatments in clinical and cosmetic practices, but reports no new clinical results.
9 citations
,
November 2017 in “Dermatologic Clinics” This article reviews botulinum toxin use in men, focusing on anatomical and treatment differences, with no new clinical results.
8 citations
,
June 2022 in “Frontiers in bioengineering and biotechnology” This study found that a collagen patch made with fibroblast-derived extracellular matrix (fdECM) extracted from human lung fibroblasts enhanced wound healing by promoting wound contraction, angiogenesis, and skin remodeling in full-thickness skin wound models, including those with diabetic ulcers.
8 citations
,
April 2020 in “Journal of Ethnopharmacology” This review assessed experimental studies on herbs used for alopecia, identifying potential mechanisms involving hair cycle management and keratinocyte processes, but highlighted a need for improved evidence on quality control and toxicity of these herbal treatments.
7 citations
,
February 2018 in “InTech eBooks” This article reviews how biomaterials and stem cells could advance regenerative medicine but does not report new results, emphasizing the potential of combining novel biomaterials with stem cells for effective therapies.
7 citations
,
August 2008 in “Cases Journal” This article reports a case of a 14-month-old child with a constriction ring syndrome caused by tightly wrapped hair, highlighting the importance of early recognition and treatment to prevent serious complications.
6 citations
,
July 2023 in “Spine Surgery and Related Research” This article reviews the potential of PRP as a treatment for spinal pain but calls for established use guidelines and protocols before wider clinical adoption, with no new clinical results reported.
6 citations
,
May 2021 in “Stem Cell Reviews and Reports” This study identified and characterized progenitor cells from equine feet that may play a role in the pathogenesis and recovery of laminitis, suggesting potential therapeutic targets for treatment.
6 citations
,
March 2021 in “Cytotechnology” This review examines recent findings on COVID-19 pneumonia treatment using mesenchymal stem cells and reports no new clinical results; the authors highlight MSCs' potential due to their immunomodulatory and tissue-regenerative properties.
6 citations
,
April 2017 in “InTech eBooks” This book discusses various unanswered questions about headaches, including genetic factors, smartphone effects, and botulinum toxin's potential benefits for chronic migraines, but reports no new clinical findings.
6 citations
,
May 2010 in “The Journal of Dermatology” A woman with anorexia developed gout from self-induced vomiting.
4 citations
,
April 2025 in “Scientific Reports” This study found that platelet-rich plasma can transiently inhibit bacterial growth in vitro against multidrug-resistant strains from diabetic foot infections, although its efficacy diminished over time and did not affect biofilm formation.
4 citations
,
October 2024 in “BMC Oral Health” This review suggests that PRF may be a promising alternative treatment for oral mucosal lesions, but further research is needed to confirm its long-term effectiveness and standardize preparation protocols.
4 citations
,
September 2024 in “Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics” This review discusses the potential of 3D cell cultures, particularly Patient-Derived Organoids, in advancing research on liposarcoma by addressing limitations of 2D cultures and animal models but reports no new experimental findings.