This case report describes a 14-year-old female with tufted hair folliculitis, where isotretinoin reduced inflammation and exudation but persistent hair tufting remained, highlighting the challenges in treating this rare condition.
December 2024 in “Medical alphabet” This article reviews current knowledge about diffuse telogen effluvium, focusing on its classification, clinical features, causes, and diagnostic and treatment approaches.
3 citations
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May 2024 in “Indian Journal of Dermatology” In this case report, researchers identified a potential adverse skin reaction, called SDRIFE or Baboon syndrome, caused by the drug tofacitinib in a 19-year-old woman being treated for alopecia subtotalis, leading the authors to recommend discontinuation of the drug.
1 citations
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January 2024 in “Arab Board Medical Journal” This study found that tofacitinib was an effective and well-tolerated treatment for alopecia areata, with significant to moderate hair regrowth in 78% of patients observed.
March 2023 in “PARIPEX INDIAN JOURNAL OF RESEARCH” This study found that prolonged tofacitinib treatment in adult Indian patients with moderate-to-severe alopecia areata was associated with a high regrowth rate, which varied with factors like age at disease onset and treatment duration.
This study observed that combining PRP and Tressfix Serum significantly improved hair regrowth and reduced microRNA expression linked to Chronic Telogen Effluvium compared to using either treatment alone.
August 2024 in “Indian Journal of Dermatology Venereology and Leprology”
November 2020 in “Dubai medical journal” This case report described a 24-year-old with alopecia totalis who saw full scalp hair regrowth by the 9th month while using oral tofacitinib, which was well-tolerated and did not show serious adverse effects. Longer-term studies are needed to confirm its overall effectiveness for alopecia totalis.
January 2026 in “Mansoura Medical Journal” This study found that patients with Telogen Effluvium had significantly higher levels of scalp pain and itching, and serum ferritin levels could effectively differentiate them from healthy controls.
November 2023 in “Indian Dermatology Online Journal” This study found that tofacitinib was safe and effective for patients with severe or treatment-resistant alopecia areata, alopecia totalis, and alopecia universalis, resulting in significant hair regrowth for most participants.
March 2020 in “Section 5: Patient safety and quality assurance” This study found that tofacitinib and baricitinib had an acceptable adverse reaction profile when used to treat rheumatoid arthritis, with similar side effects to those described in their technical data sheets.
September 2025 in “Annals of African Medicine” 2 citations
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June 2020 in “Clinical Journal of Gastroenterology” This case report describes two patients with ulcerative colitis and alopecia areata who did not respond to various treatments but achieved remission and improved hair growth after starting tofacitinib.
December 2022 in “Zenodo (CERN European Organization for Nuclear Research)” In this report, a 14-year-old female with stubborn alopecia areata was successfully treated with oral tofacitinib, indicating its potential effectiveness for severe cases.
23 citations
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January 2016 in “Frontiers in immunology” This review discusses the potential of combining low-dose IL-2 with islet antigens to enhance antigen-specific Treg function in type 1 diabetes, but reports no new clinical results.
January 2018 in “International journal of medical biochemistry” This study found that female patients with telogen effluvium had significantly lower levels of serum ferritin, folate, and vitamin B12 compared to the control group.
24 citations
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August 2019 in “Journal of the American Academy of Dermatology” Teledermatology reduces unnecessary in-person visits and improves care.
28 citations
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December 2017 in “Journal of Investigative Dermatology Symposium Proceedings” This review summarizes findings on the long-term use of tofacitinib for severe alopecia areata, reporting its potential as a promising treatment option.
This study found that tenuazonic acid from Alternaria alternata can cause significant damage to vital organs in mice at low doses and highlights the need for regulatory measures to manage its risk in agricultural products.
1 citations
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January 2022 in “Skin appendage disorders” This case series reported that telogen effluvium may reveal underlying traction alopecia, emphasizing the importance of recognizing this to ensure accurate diagnosis and treatment.
17 citations
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January 2019 in “Dermatologic Therapy” The article in Dermatologic Therapy discusses clinical experiences with using tofacitinib to treat alopecia areata in 63 patients, but no specific results are reported in the abstract.
5 citations
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September 2020 in “Proceedings - Baylor University. Medical Center” In this case report, a 39-year-old woman's symptoms from dermatomyositis–systemic lupus erythematosus overlap syndrome improved only after she was treated with tofacitinib.
June 2019 in “Journal of Medical Sciences” This study found that female patients with telogen effluvium had significantly lower serum ferritin levels compared to healthy individuals, suggesting an association between low ferritin and this condition.
September 2022 in “PubMed” Entadfi, a mix of finasteride and tadalafil, is used for BPH.
2 citations
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November 2023 in “Acta dermato-venereologica” This study involving 126 patients found that tofacitinib has high effectiveness and an acceptable safety profile for treating alopecia areata, with a 33.8% complete response rate at 24 weeks and sex as an independent risk factor for outcomes.
32 citations
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April 2006 in “The Journal of Urology” Using finasteride with TIP extends time off period for prostate cancer patients.
February 2025 in “Journal of Cosmetic Dermatology” In this study, researchers observed that deficiency in biochemical markers, notably ferritin and serum iron, is frequently found in female patients diagnosed with telogen effluvium, suggesting these tests are crucial in understanding and treating the condition.
July 2025 in “Clinical Medicine” In this institution-based randomized trial, oral betamethasone mini-pulse therapy for alopecia areata showed a faster therapeutic response compared to oral tofacitinib, as measured by trichoscopic changes and achievement of 50% hair regrowth.
July 2025 in “International Journal of Trichology” This study reported that six out of seven pediatric patients with refractory patchy alopecia areata experienced significant hair regrowth after one month of oral tofacitinib treatment, suggesting it may be an effective and safe option, although larger studies are needed to evaluate long-term safety.
8 citations
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July 2020 in “Dermatologic Therapy” Tofacitinib may effectively treat folliculitis decalvans.