Oral Tofacitinib in Refractory Pediatric Alopecia Areata

    Priyadarshini Mishra, Namrata Nidhi, Binayak Chandra Dwari, Nibedita Patro
    TLDR Oral tofacitinib may effectively regrow hair in children with alopecia areata unresponsive to other treatments.
    This case series examined the effects of oral tofacitinib on 7 pediatric patients with refractory alopecia areata. The study revealed that 5 out of 7 children experienced over 50% improvement in their SALT scores after 8 weeks of treatment, indicating significant hair regrowth. The treatment was well-tolerated with no adverse effects reported. These results suggest that oral tofacitinib is a promising and safe alternative for treating pediatric alopecia areata, though further research is necessary to evaluate long-term safety and efficacy.
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