Refractory Dermatomyositis–Systemic Lupus Erythematosus Overlap Syndrome and Response to Tofacitinib

    Preston Williams, Benjamin McKinney
    TLDR Tofacitinib successfully treated a woman's severe symptoms from a rare autoimmune condition.
    A 39-year-old woman with dermatomyositis–systemic lupus erythematosus overlap syndrome experienced severe symptoms including a facial rash, arthralgias, lower-extremity edema, proximal muscle weakness, and hair loss over a 2.5-month hospitalization. Her symptoms were resistant to initial treatments but eventually resolved with the administration of tofacitinib.
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