September 2023 in “Pharmaceuticals” This study found that nanoparticles containing minoxidil and betamethasone improved drug delivery to hair follicles, with lipidic nanoparticles significantly enhancing minoxidil and betamethasone penetration compared to control, making them a promising option for alopecia areata treatment with reduced side effects.
January 2017 in “Springer eBooks” The document explains various skin conditions and their treatments.
January 2022 in “Stem cell biology and regenerative medicine” This review explores the complex interactions between hair follicle stem cells and surrounding structures that are essential for understanding hair regeneration, reporting no new experimental results.
75 citations
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February 2017 in “Aging” This study found that treating mtDNA mutator mice with the antioxidant SkQ1 delayed aging traits and extended their lifespan, potentially by alleviating mitochondrial dysfunction caused by reactive oxygen species.
61 citations
,
September 2010 in “Genomics” This study found distinct gene expression profiles in alopecia areata-affected skin, suggesting T-cell mediated immune responses and unique gene profiles between different stages of the disease.
22 citations
,
May 2007 in “Molecular Biotechnology”
3 citations
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January 2019 in “Jikken doubutsu ihou/Jikken doubutsu/Experimental animals/Jikken Dobutsu” This study reported that knocking out the HR gene in pigs using CRISPR/Cas9 led to hairless eyelids and abnormalities in the thymus and peripheral blood, suggesting pigs as a model for human HR-related hair disorders.
1 citations
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November 2025 in “Science Advances” This research identified two genetic variants that influence the white-spotted coat patterns in Holstein-Friesian cattle, involving regulatory changes in the MITF and KIT genes, confirmed through mouse models, along with possible effects on coat patterns in other cattle breeds.
June 2026 in “Frontiers in Aging” This study introduces "Homeodynamic Rejuvenation" as a method to restore the skin's resilience by enhancing its ability to detect and recover from stress, focusing on five core biological processes critical for maintaining skin function and health amidst environmental and metabolic challenges.
January 2026 in “Dermatology and Therapy” This study suggests a possible bidirectional relationship between sleep quality and hair loss, indicating that addressing sleep disturbances might improve hair loss management and patient well-being.
October 2025 in “Progress In Microbes & Molecular Biology” This review reveals that PCOS is consistently linked to gut microbiota dysbiosis, characterized by reduced microbial diversity and shifts in composition, which are associated with various PCOS phenotypes and may present opportunities for microbiota-targeted therapies addressing the disorder's underlying pathophysiological mechanisms.
August 2025 in “Dermatology and Therapy” This study conducted a meta-analysis of gene expression data from alopecia areata patients, identifying 5109 differentially expressed genes and highlighting enriched pathways like JAK-STAT signaling, providing insights into the disease's pathogenesis and potential treatment targets.
February 2026 in “International Journal of Molecular Sciences” In this review, researchers discuss how mitochondria-targeted biophysical priming of autologous biologics, through methods like photobiomodulation and ultrasound, can potentially enhance skin rejuvenation and wound repair by modulating mitochondrial function in skin cells.
August 2025 in “Archiv Euromedica” This review explored the relationship between alopecia areata and gut microbiota imbalances, noting potential immune dysregulation due to microbiome alterations. It highlighted promising results from fecal microbiota transplantation in treating alopecia universalis, indicating a need for further research into microbiome-targeted therapies.
278 citations
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May 2013 in “Ca” This review discusses the shift in toxicity profiles of cancer therapies from traditional chemotherapy to targeted agents, noting similar overall toxicities but with different side effects, and reports no new findings.
54 citations
,
June 2020 in “Pharmaceutics” This review discusses the advancements in using "soft" colloidal nanocarriers for delivering photosensitive agents and highlights their potential applications in treating diseases like cancer, but it reports no new clinical results.
54 citations
,
September 2012 in “Acta ophthalmologica” This review highlights that various targeted cancer therapies are associated with specific ocular side-effects, emphasizing the importance of awareness among ophthalmologists for timely diagnosis and management.
52 citations
,
September 2022 in “Viruses” This review discusses the functions of SARS-CoV-2 non-structural proteins in facilitating immune evasion and highlights possible therapeutic strategies, reporting no new clinical results.
7 citations
,
September 2020 in “Bioscience Biotechnology and Biochemistry” This study found that bacterial community structures on hair and scalp differ significantly, with distinct abundances of Pseudomonas on hair and Staphylococcus on scalp.
4 citations
,
October 2024 in “Heliyon” This study characterized the CYP154C7 enzyme from *Streptomyces* sp. PAMC26508, highlighting its ability to hydroxylate steroids efficiently, particularly androstenedione, and identified key amino acids important for substrate selectivity and catalytic efficiency.
4 citations
,
July 2023 in “Pharmaceutics (Basel)” This study reviews various skin models and methodologies used to assess the follicular penetration of nanoparticle-based drugs, highlighting inconsistencies that complicate comparisons and aims to establish more uniform protocols for clearer study outcomes.
3 citations
,
May 2024 in “Biomimetics” This narrative review examines the structure-function relationship in bioactive biopolymers used to promote healing in chronic wounds, emphasizing diabetic ulcers, and underscores the importance of characterizing these biopolymers to enhance their bioactivity for better tissue regeneration outcomes.
This review synthesizes current knowledge on choriogenesis, the final stage of oogenesis in insects, by exploring the role of follicle cells, regulatory mechanisms of gene expression, and the biochemical makeup of the eggshell, while also highlighting structural diversity and adaptations across insect species.
This review summarizes the composition, bioactive functions, and potential industrial applications of rice bran polysaccharides, focusing on how extraction methods and modifications impact their biological activities.
January 2023 in “Kafkas üniversitesi veteriner fakültesi dergisi/Kafkas üniversitesi veteriner fakültesi dergisi” In this study of Angora goats, researchers found that HOXC13 and other genes were overexpressed during the active hair growth phase, suggesting a role in mohair structure.
March 2012 in “Journal of the American Academy of Dermatology” African Americans lack knowledge about laser hair removal safety, Nd:Yag laser treatment is effective with high satisfaction, pressure during surgery can cause hair loss, and treating ovarian inflammation may help with alopecia areata.
48 citations
,
April 2023 in “Aging Cell” This review discusses cellular senescence in human skin, detailing both beneficial and detrimental effects and suggesting the potential for therapies targeting senescence-related skin disorders, but reports no new clinical results.
20 citations
,
May 2023 in “Cancer Nanotechnology” The researchers reported that their novel formulation of pterostilbene-loaded ethoniosomes with folic acid coating effectively targeted lung cancer cells in vitro and demonstrated promising results in animal models, indicating potential for future targeted chemotherapy applications.
12 citations
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February 2017 in “Journal of neuroscience research” This study suggests that extrasynaptic δGABA-A receptors may have a protective role in modulating the severity of catamenial-like seizures by influencing neurosteroid and benzodiazepine responses in mice.
9 citations
,
July 2024 in “Toxins” This opinion article reviews various pathways through which onabotulinumtoxinA might work in medical treatments, highlighting applications beyond muscle paralysis, including pain inhibition and potential effects on hair loss and cancer cell apoptosis.