Gut Microbiota and Autoimmune Alopecia Areata: Current Insights from the Literature
August 2025
in “
Archiv Euromedica
”
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Studysummary This review explored the relationship between alopecia areata and gut microbiota imbalances, noting potential immune dysregulation due to microbiome alterations. It highlighted promising results from fecal microbiota transplantation in treating alopecia universalis, indicating a need for further research into microbiome-targeted therapies. Our plain-language summary of this paper — not a Tressless recommendation.
Recent insights suggest that disturbances in the gut microbiota may contribute to the pathogenesis of alopecia areata (AA) by affecting immune regulation. This review analyzed literature indicating that alterations in the gut microbiome of AA patients could be linked to immune dysregulation. Promising outcomes from fecal microbiota transplantation (FMT) in cases of alopecia universalis underscore the potential for microbiome-targeted therapies in treating AA, warranting further research in this area.
