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T cells and bacteria in the gut and skin help maintain health and protect against disease.

The study found that immune responses disrupt hair growth cycles, causing hair loss in alopecia areata.

Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.

Malt1 protease is essential for regulatory T cell function and could be targeted to boost antitumor immunity.

The document concludes that more research is needed to better understand and treat primary cicatricial alopecias, and suggests a possible reclassification based on molecular pathways.

EGCG may help treat alopecia areata by blocking certain immune responses and reducing specific harmful immune cells.

Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.

Epidermal keratinocytes start wound healing and inflammation after schistosome infection.

Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.

An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.

Cell therapy shows promise for treating severe psoriasis but needs more research to confirm safety and effectiveness.

TNC+ fibroblasts play a key role in skin inflammation by interacting with T cells.

Sebaceous glands play a key role in skin health, immunity, and various skin diseases.

The reviewers found the manuscript on inflammation's role in cancer stem cells to be relevant but suggested it needs clarity, more background information, discussion on immune cells' role in tumors, updated references, and grammar corrections.

The reviewers suggest clarifying the abstract, adding background on inflammation's effect on stem cells and cancer, discussing immune cells' role in tumors, and considering inflammation's potential to reduce cancer growth.

The reviewers suggest clarifying and expanding on the role of inflammation in stem cell-related cancer development.

The revised study on how inflammation affects cancer stem cells was accepted after improving clarity and structure.

Reviewers suggest clarifying the abstract, adding background on inflammation's effect on cancer, discussing immune cell roles, including counter studies, and correcting grammar.

The revised manuscript on how inflammation affects cancer stem cells was accepted after addressing issues with clarity and detail.

The secretome from mesenchymal stem cells is a promising treatment that may repair tissue and avoid side effects of stem cell transplantation.

Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.

Current and future treatments for alopecia areata focus on immunosuppression, immunomodulation, and protecting hair follicles.

Researchers found a specific immune receptor in patients that causes severe skin reactions to a drug.

Understanding the immune-related causes of Alopecia Areata has led to potential treatments like JAK inhibitors.

Hair growth phase and certain genes can speed up wound healing, while an inflammatory mediator can slow down new hair growth after a wound. Understanding these factors can improve tissue regeneration during wound healing.

Alopecia areata shows a unique type 1 interferon signature, suggesting potential treatment by targeting this pathway.

Activating TLR9 helps heal wounds and regrow hair by using specific immune cells.

Immune checkpoint inhibitors can cause skin issues but are linked to better cancer outcomes.

The document concludes that pregnancy and cancer share immune evasion tactics, but more research is needed before using checkpoint blockade immunotherapy in pregnant cancer patients to avoid harm to the placenta.

A protein called lfTSLP is important in causing allergic and other skin diseases and could be a target for treatment.