28 citations
,
January 2012 in “International Journal of Trichology” This study observed that specific trichoscopic features like white peripilar signs, scalp pigmentation, and focal atrichia are associated with advanced female pattern hair loss in Fitzpatrick skin type III patients.
28 citations
,
April 2009 in “Annals of laboratory medicine” This study found that the DFS pattern occurs in about 28% of ANA-positive cases and is relatively frequent in autoimmune diseases, contrary to previous observations suggesting no link with these diseases.
28 citations
,
March 2007 in “Journal of The European Academy of Dermatology and Venereology” In this study, researchers found that the existing Norwood and Hamilton classifications for androgenetic alopecia in Indian males had significant limitations, with 18% of cases not fitting into existing pattern categories.
27 citations
,
May 2007 in “Archives of dermatological research” In this study, alopecia areata patients treated with diphencyprone showed a significant increase in CD8 lymphocytes around hair bulbs, which may be associated with hair regrowth.
26 citations
,
January 2019 in “Experimental Dermatology” This study developed an in vitro system to analyze human skin progenitor cells' ability to form hair peg-like structures, providing insights for engineering hair follicle organoids.
26 citations
,
December 2015 in “Journal of The European Academy of Dermatology and Venereology” This article introduces a new grading system called the FPHL Severity Index to better identify and monitor early stages of female pattern hair loss using clinical criteria.
25 citations
,
January 1998 in “Dermatology” Male pattern hair loss negatively affects quality of life, but drug treatments can help.
24 citations
,
January 2012 in “Indian Journal of Dermatology, Venereology and Leprology” This study suggests that hypersensitivity and increased serum IgE levels might contribute to the pathogenesis of diffuse alopecia areata through intense local inflammatory infiltration.
23 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” This article reviews the pathophysiology, diagnosis, and treatment of female pattern hair loss, highlighting the importance of early medical intervention to arrest hair loss progression, but reports no new clinical results.
22 citations
,
March 2020 in “Journal of The American Academy of Dermatology” This study found that injecting autologous dermal sheath cup cells significantly increased hair density and diameter in male and female pattern hair loss compared to a placebo for up to 9 months.
22 citations
,
May 2013 in “Experimental and Therapeutic Medicine” This study found that topical minoxidil improved the quality of life in female patients with pattern hair loss.
21 citations
,
May 2016 in “The Cochrane library” This review found that while topical minoxidil is effective for treating female pattern hair loss, finasteride showed no more effectiveness than placebo, and low-level laser therapy increased hair count but with inconsistent results.
21 citations
,
April 2016 in “International Journal of Dermatology” This study found a significant association between female pattern hair loss and metabolic syndrome in Egyptian women, with waist circumference and hypertension particularly linked to the severity of hair loss.
21 citations
,
January 2012 in “Annals of Dermatology” This study reported that Ell-Cranell® alpha 0.025% solution significantly increased hair counts and diameter in Korean women with female pattern hair loss over an 8-month period, showing both efficacy and safety.
21 citations
,
June 2009 in “Current Medical Research and Opinion” In this study, men seeking treatment for male pattern hair loss were highly concerned about their condition and had often attempted self-treatment, but many were dissatisfied with their physician consultations due to unmet expectations and perceived indifference from doctors.
21 citations
,
January 2007 in “Australasian Journal of Dermatology” This case report describes how a 53-year-old woman with female pattern hair loss experienced further hair regrowth when topical minoxidil was added to her spironolactone treatment after initial results plateaued.
21 citations
,
January 2000 in “Aesthetic Plastic Surgery” This study introduced a new classification method for male pattern baldness in Korean men, detailing six types that could guide hair restoration surgery and further research.
20 citations
,
September 2021 in “Nature communications” In this study, researchers identified a gene expression pre-pattern and implicated the Wnt inhibitor Dickkopf 4 in the formation of color patterns in domestic cat embryos.
20 citations
,
December 2008 in “PubMed” In this study, treatment with finasteride 1 mg/day for five years significantly reduced the likelihood of further visible hair loss in men with androgenetic alopecia compared to placebo.
19 citations
,
April 2015 in “Developmental Dynamics” This study reports that dynamic interactions between stem cells and their niche, influenced by macro-environmental factors, regulate regenerative behavior in integument pattern formation.
19 citations
,
November 2012 in “BJUI” In this study, researchers observed that the sexual effects of dihydrotestosterone deprivation using finasteride may vary by handedness, with right-handed men often experiencing lower sexual function and left-handed men showing no effect or improvement.
19 citations
,
February 2008 in “Archives of Dermatological Research” This study observed that mast cells and increased collagen and elastic fibers in the scalp may contribute to male pattern hair loss, but additional research is needed for further understanding.
19 citations
,
August 2000 in “International Journal of Dermatology” This article discusses the medical management of male pattern hair loss and reports no new clinical findings.
18 citations
,
January 2017 in “Annals of dermatology/Annals of Dermatology” This study found that Th17 lymphocytes may play a more crucial role than cytotoxic T cells in the development of alopecia areata due to their infiltration around the hair bulb/bulge, which exacerbates hair loss as histopathological grade worsens.
18 citations
,
February 2012 in “Experimental Dermatology” This study found no significant association between selected gene variants and female pattern hair loss, suggesting these genes might not be involved in its development.
18 citations
,
January 2008 in “Journal of The American Academy of Dermatology” This study found that the proteins GDNF, NTN, GFRα-1, GFRα-2, and c-Ret are differentially expressed during various stages of the human hair follicle cycle, with potential implications for hair biology.
17 citations
,
January 2016 in “American Journal of Epidemiology” This study suggests that any baldness, particularly moderate balding, is associated with a higher risk of fatal prostate cancer in men, supporting a possible link between hair loss and prostate cancer mechanisms.
17 citations
,
June 2001 in “Journal of the National Cancer Institute” A specific hair diffraction pattern may indicate breast cancer if tested with the correct method.
16 citations
,
May 2020 in “Journal of The European Academy of Dermatology and Venereology” This publication involves a case-series report on the treatment of male and female pattern hair loss using sublingual minoxidil in 64 patients, but it does not include an abstract or results.
16 citations
,
July 2016 in “Veterinary Dermatology” This study found that dermoscopy can identify distinctive features in canine pattern alopecia, such as hair shaft thinning and pigmentation patterns, which may aid in diagnosing this and potentially other skin disorders.