research Alopecia in General Medicine
The document concludes that diagnosing and treating hair loss is complex and requires understanding its psychological effects and underlying causes, while also calling for more research and new treatments.
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research Failure to Induce Alopecia Areata in C3H/HeJ Mice with Exogenous Interferon Gamma
Interferon gamma alone can't cause alopecia areata in C3H/HeJ mice.
research Veterinary Pharmacology
Some plant extracts may treat livestock diseases, certain animal treatments are safe and effective, but more research on drug safety and resistance is needed.
research Systemic Lupus Erythematosus: Definitions, Contexts, Conflicts, Enigmas
The document concludes that anti-dsDNA antibodies are not unique to SLE and their use as indicators is doubtful, highlighting the need for better understanding and classification of the disease.
research Hair Follicle Mesenchyme-Associated PD-L1 Regulates T-Cell Activation Induced Apoptosis: A Potential Mechanism of Immune Privilege
Hair follicle cells help protect against immune attacks by regulating T-cell activity.
research Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis
FOXN1 gene variants cause low T cells and immune issues from birth.
research High-Throughput T Cell Receptor Sequencing Identifies Clonally Expanded CD8+ T Cell Populations in Alopecia Areata
CD8+ T cells are involved in alopecia areata and may cause disease relapse.
research T Cell–Mediated Acute Localized Exanthematous Pustulosis Caused by Finasteride
Finasteride caused a rare skin rash in a man, which improved after stopping the medication.
research Alopecia Areata But Not Androgenetic Alopecia Is Characterized By A Restricted And Oligoclonal T-Cell Receptor-Repertoire Among Infiltrating Lymphocytes
Alopecia areata involves specific T-cells, unlike androgenetic alopecia.
research MmuPV1 Infection and Tumor Development in T Cell-Deficient Mice Prevented by Passively Transferred Hyperimmune Sera from Normal Congenic Mice Immunized with MmuPV1 Virus-Like Particles
Giving immune serum from vaccinated mice to mice without T cells prevents infection and tumor growth.
research Induction of T Cell Exhaustion by JAK1/3 Inhibition in the Treatment of Alopecia Areata
Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.
research Evaluation of Platelet-Rich Plasma on Hair Regrowth and Lesional T-Cell Cytokine Expression in Alopecia Areata: A Randomized Observer-Blinded, Placebo-Controlled, Split-Head Pilot Study
Platelet-rich plasma may help restore immune balance in bald patches, but its effectiveness in treating hair loss is limited.
research Androgenetic Alopecia May Be Associated With Weaker COVID-19 T-Cell Immune Response: An Insight Into a Potential COVID-19 Vaccine Booster
Hair loss may link to weaker COVID-19 immunity, suggesting possible need for extra vaccine boost.
research T-Cell Induced-Self MHC Class I/Peptide Complexes May Enable De Novo Tolerance Induction to Neo-Antigens Occurring Outside of the Thymus
Hair follicles may help teach the immune system to tolerate new self-antigens, but this can sometimes cause hair loss.
research T-Cell Reconstitution After Thymus Xenotransplantation Induces Hair Depigmentation and Loss
T-cell reconstitution after thymus transplantation can cause hair whitening and loss.
research Impaired Responses of Peripheral Blood Mononuclear Cells to T-Cell Stimulants in Alopecia Areata Patients with a Poor Response to Topical Immunotherapy
Poor response to topical immunotherapy in alopecia areata patients is linked to impaired cell responses.
research High Throughput T Cell Receptor Sequencing Identifies Clonally Expanded CD8+ T Cell Populations in Alopecia Areata
Expanded CD8+ T cells are linked to Alopecia Areata and may cause relapse after treatment.
research Expression of Programmed Cell Death 1 Inversely Correlated With the Density of CD8+ T Cells Infiltrating Hair Follicles in Alopecia Areata
Higher PD-1 levels are linked to fewer immune cells in hair follicles in alopecia areata.
research T Cell and Bacterial Microbiota Interaction at Intestinal and Skin Epithelial Interfaces
T cells and bacteria in the gut and skin help maintain health and protect against disease.
research Chronic Urticaria Versus Dermatomyositis in a Case of T-Cell Large Granular Lymphocytic Leukemia
The muscle damage was caused by T-cell large granular lymphocytic leukemia, not dermatomyositis.
research Immunohistochemical Analysis of T-Cell Subsets in the Inflammatory Infiltrates of Alopecia Areata and Its Comparison with Androgenetic Alopecia
T-cell patterns in skin help distinguish alopecia areata from androgenetic alopecia.
research Skin Aging and Hair Follicle Stem Cell Dysfunction Caused by T Cells With Defective Mitochondrial Metabolism
Defective T cell metabolism can cause early skin aging and poor hair follicle stem cell function.
research Hair Follicle-Derived IL-7 and IL-15 Mediate Skin-Resident Memory T Cell Homeostasis and Lymphoma
Hair follicle-derived IL-7 and IL-15 are crucial for maintaining skin-resident memory T cells and could be targeted for treating skin diseases and lymphoma.
research Interferon Alfa-2a in the Treatment of Cutaneous T Cell Lymphoma
Interferon alfa-2a is effective for treating cutaneous T cell lymphoma but has significant side effects.
research Interferon in the Treatment of Cutaneous T-Cell Lymphoma
Interferon, especially alfa interferon, is an effective treatment for cutaneous T-cell lymphoma with manageable side effects.
research T Helper 17 Cell/Regulatory T-Cell Imbalance in Hidradenitis Suppurativa/Acne Inversa: The Link to Hair Follicle Dissection, Obesity, Smoking, and Autoimmune Comorbidities
An imbalance between certain immune cells is linked to a chronic skin condition and may be influenced by obesity, smoking, and autoimmune issues.
research Current Management Strategies for Cutaneous T-Cell Lymphoma
The document concludes that treatment for cutaneous T-cell lymphoma should be customized to each patient's disease stage, balancing benefits and side effects, with no cure but many patients living long lives.
research Phase II Evaluation of VDC-1101 in Canine Cutaneous T-Cell Lymphoma
VDC-1101 shows potential as a treatment for canine cutaneous T-cell lymphoma.
research Alopecia Universalis Associated with Cutaneous T Cell Lymphoma
Some patients with a type of skin lymphoma can experience a rare, non-scarring hair loss that looks like another hair loss condition but has distinct features.
research Cutaneous T-Cell Lymphoma
The document concludes that DAB389-IL2 is promising for treating refractory cutaneous T-cell lymphoma, but more research is needed on its effectiveness and side effect management.