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This study suggests that vitamin A may inhibit hair follicle stem cells during refractory telogen in a dose-dependent manner, based on retinyl ester levels and vitamin A metabolism protein localization in mice.

This review examines the role of cannabinoid compounds in treating various skin conditions and suggests their potential as systemic and topical therapies, but it reports no new experimental results.

In this randomized study, BAY 1158061, a prolactin receptor antibody, was found to be safe, well-tolerated, and exhibited low immunogenicity in healthy postmenopausal women, but had no effect on serum prolactin levels compared to placebo.

This study concluded that fenugreek seed extract loaded solid lipid nanoparticles demonstrated enhanced skin retention and extended release, suggesting potential as a future alternative treatment for alopecia.

The document concludes that more research is needed to better understand and treat scarring hair loss conditions.

This study found that dutasteride-loaded transfersomes, compared to traditional liposomes, better target hair follicles by releasing the drug in a more controlled manner, as shown in vitro with enhanced follicular targeting (Tf = 0.32 versus 0.15, p < 0.005) using porcine ear skin.

In this rodent model study, the researchers reported that using low-intensity focused ultrasound with phenytoin enhanced its anti-epileptic efficacy by disrupting plasma protein binding in a region-specific manner, reducing seizure frequency and duration.

In this study, the novel isoprenylcysteine analog SIG-1451 was shown to inhibit pro-inflammatory cytokine release in various cell-based assays relevant to allergic dermatitis, acting on targets such as IL-4 and IL-6 with potential anti-inflammatory benefits.

Scientists found gene mutations that affect hair loss, skin stem cells, and skin disorders, and identified drugs that may help treat blood vessel and skin conditions.

This study reports that incomplete information in a reverse supply chain can lead to efficiency losses, but a two-part tariff contract for the remanufacturer may improve performance by eliciting private information from collectors.

This study found that prolactin and its receptor are expressed in the murine hair follicle epithelium, influencing hair cycle phases by down-regulating keratinocyte proliferation during anagen and inducing premature catagen.

This study describes the enzymatic processes through which DHEA is converted to active sex steroids in human skin, highlighting an androgenic effect on sebaceous glands and estrogenic effects in the vagina.

In this study, researchers found that tritiated cortisol was incorporated into the hair of rhesus monkeys primarily as cortisol and cortisone, as well as other metabolites, after systemic administration.

This article discusses the history and terminology of toxic epidermal necrolysis but reports no new clinical results.

This review discusses baricitinib's applications for various inflammatory disorders and highlights its promising efficacy alongside potential adverse effects, advocating for further research before it becomes a standard treatment.

This review discusses diagnostic and treatment considerations for women with cutaneous hyperandrogenism, noting therapeutic options are more effective for hirsutism and acne than for androgenetic alopecia, but reports no new clinical results.

This study found that a novel IKZF1 mutation, p.L188V, is linked to juvenile-onset systemic lupus erythematosus and alters B-cell activation by disrupting normal DNA binding.

This study suggests that prolactin has complex, gender- and location-dependent effects on human hair follicles, promoting hair growth in female frontotemporal scalp areas while inhibiting it in male occipital regions.

This article reviews anthralin's pharmacology, mode of action, and its use for psoriasis and other dermatoses, but reports no new clinical results.

This review explores the use of skin penetration enhancers like Transcutol® in various formulation systems, discussing their mechanisms and effectiveness in improving transdermal drug delivery without breaching the skin.

This review highlights the potential of scaffold-based drug delivery systems to revolutionize oral cancer treatment by enhancing targeted and localized drug administration, reducing systemic side effects, and providing environments conducive to non-cancerous cell growth, though challenges like scalability and biocompatibility remain.

This study found that minoxidil absorption through the skin increased with longer contact times, reaching over 75% of the maximum absorption within four hours.

This case report describes hair regrowth in a patient with alopecia totalis using fluocinolone acetonide cream applied under thin plastic films.

This study found that dutasteride completely suppressed the formation of 5alpha-dihydro metabolites in cultured human skin cells, suggesting its potential use in acne and androgenetic alopecia.

In this study, magnesium was observed to penetrate human skin, with hair follicles significantly aiding this process depending on the concentration and duration of exposure.

This study found that glycine treatment inhibited melanogenesis in B16F0 melanoma cells and reduced melanin content in C57BL/6J mice by down-regulating tyrosinase protein levels.

This study found that a cream containing spironolactone did not affect hair growth in hirsute women.

In this ex vivo and mouse model study, Tofacitinib-loaded nanoparticles demonstrated enhanced delivery of the drug into hair follicles and reduced inflammatory effects compared to conventional forms, indicating potential for safer, topical use in treating alopecia areata.

This study found that human placenta hydrolysate reduced SARS-CoV-2 replication and improved immune response in ferret models, suggesting potential as a COVID-19 treatment.

This study observed that the compound EM-402 reduced 5α-reductase activity and sebaceous gland size in the flank organs and ears of hamsters, indicating potent localized anti-androgenic effects without systemic action.