13 citations
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April 2020 in “Dermatology and therapy” This systematic review assessed cyclosporine's effectiveness with or without corticosteroids for treating alopecia areata, finding combined therapy more effective and with a lower recurrence rate than monotherapy, especially for severe cases, though results varied by alopecia type.
6 citations
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March 2019 in “International Journal of Molecular Medicine” This study found that finasteride-loaded microspheres effectively treated androgenic alopecia in a mouse model, showing similar hair growth effects to orally-administered finasteride.
June 2026 in “Eurasian Journal of Medicine” Baricitinib effectively regrew hair in a woman with alopecia universalis after other treatments failed.
June 2017 in “Journal of The American Academy of Dermatology” Tapinarof cream at 1% concentration is effective and better tolerated for treating atopic dermatitis than the 2% concentration.
37 citations
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November 1995 in “Journal of Investigative Dermatology” This study found that topical finasteride and flutamide both significantly reduced sebaceous gland growth and decreased prostatic weights in hamsters, indicating systemic effects despite local application.
26 citations
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March 2015 in “American journal of clinical dermatology” This study found that systemic mycophenolate mofetil and topical clobetasol were equally effective at reducing lichen planopilaris activity over six months, but satisfaction differed between the treatments.
18 citations
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January 2017 in “Journal der Deutschen Dermatologischen Gesellschaft” This study reports that sequential high- and low-dose prednisolone therapy effectively promotes complete hair regrowth in 62% of children with severe alopecia areata, while minimizing severe side effects.
8 citations
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January 2008 in “Annals of Dermatology” This study concluded that combining systemic cyclosporine A with low-dose corticosteroids effectively treats severe alopecia areata while maintaining safe cyclosporine A levels in the blood.
16 citations
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April 2006 in “Pediatrics International” This study reported that high-dose mizoribin therapy may be effective and safe for managing steroid-dependent pediatric systemic lupus erythematosus but requires monitoring of serum uric acid levels due to potential side effects.
5 citations
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November 2023 in “The Journal of Dermatology” This study found that anifrolumab effectively reduced disease activity and allowed for corticosteroid tapering in patients with systemic lupus erythematosus at Kanazawa University Hospital.
3 citations
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July 2024 in “Archives of Dermatological Research” This study found that oral dexamethasone and DPCP were more effective for treating severe alopecia areata compared to oral ritlecitinib and baricitinib, but oral ritlecitinib had better safety outcomes.
December 2025 in “Asian Journal of Advanced Research and Reports” This study found that measuring stress biomarkers in hair could be an effective and simpler method for assessing chronic stress in rats, potentially offering a novel alternative to serum tests with biomarkers including sodium, calcium, and cortisol.
In this multicenter study, belimumab effectively reduced disease activity in systemic lupus erythematosus patients with joint and skin manifestations, showing significant improvement in acute and subacute skin types earlier than in chronic types, while no significant benefit was observed for nonspecific skin manifestations.
January 2012 in “Yearbook of Dermatology and Dermatologic Surgery” Taking finasteride daily can effectively and safely increase hair density and thickness for women with hair loss.
14 citations
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June 1982 in “Archives of Dermatology” This letter to the editor shares concerns about possible systemic effects from topical dinitrochlorobenzene therapy in a 25-year-old man treating alopecia areata.
July 2026 in “International Journal of Applied Pharmaceutics” This review discusses the dermatological and systemic adverse effects of hair dye use, particularly focusing on the common allergen para-phenylenediamine, and reports no new clinical data.
41 citations
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September 2018 in “Australasian journal of dermatology” This review suggests that oral prednisolone pulse therapy and oral inosiplex may be effective for alopecia areata, but robust evidence from randomized controlled trials is lacking, highlighting the need for better-designed future studies.
37 citations
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January 2015 in “Journal of Clinical and Experimental Dentistry” This animal study found that both systemic and topical forms of Zizyphus jujuba extract were associated with reduced severity of oral mucositis in golden hamsters treated with 5-fluorouracil.
3 citations
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January 2012 in “Shijie zhongxiyi jiehe zazhi” In this study, compound zishenqing formula combined with standard medications improved symptoms and immune indices in female SLE patients, with a lower occurrence of side effects compared to standard medications alone.
February 2013 in “Journal of The American Academy of Dermatology” Hair loss is a common but often unreported side effect of cancer treatments, especially for breast and prostate cancers.
March 2026 in “RS Global journals (RS Global Sp. z O.O.)” This review reports that while finasteride effectively treats androgenetic alopecia and benign prostatic hyperplasia, persistent adverse effects on sexual, psychological, and metabolic health have been noted, highlighting the need for ongoing research and careful risk assessment for safer clinical usage.
11 citations
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December 2017 in “Journal of the American Academy of Dermatology” This letter highlights that levonorgestrel intrauterine devices may lead to fewer systemic side effects, like acne, compared to its oral administration due to lower systemic levels of progestogens.
11 citations
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March 2019 in “Journal of The American Academy of Dermatology” This review identifies evidence of sexual adverse effects, particularly linked to finasteride, in men using systemic dermatologic medications but reports no new clinical findings.
5 citations
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November 1992 in “Current problems in dermatology” This review discusses the role of glucocorticoids in treating severe inflammatory disorders and highlights their potential adverse effects, recommending dosage management to minimize these risks; no new clinical results are reported.
This study observed that in a real-world clinical setting in Greece, belimumab effectively controlled disease activity in lupus patients and allowed for a reduction in glucocorticoid dosage, with more pronounced benefits seen in patients who were serologically active at the start of treatment.
1 citations
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May 2024 in “International journal of medicine and psychology.” In this study, researchers found that using electromagnetic radiation in the EHF range enhanced the engraftment of skin flaps in rats by improving microcirculation and reducing necrosis, with greater effects observed when paired with systemic ozone therapy.
1 citations
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June 2021 in “Journal of dermatology and dermatitis” This review explores the promising but varied effectiveness of tyrosine kinase inhibitors for treating different skin diseases, indicating their potential in dermatology while acknowledging the need for more evidence.
1 citations
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April 1993 in “Problemy e̊ndokrinologii” This article discusses hyperandrogenism syndrome in women, highlighting systemic antiandrogenic therapy as advisable for severe or moderate hirsutism but reports no new clinical results.
1 citations
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June 2018 in “Journal of General-Procedural Dermatology & Venereology Indonesia” This case study reports that combining skin debridement with topical and systemic antifungals improved treatment outcomes for kerion celsi in a 5-year-old boy, preventing scarring alopecia.
May 2026 in “Indian Journal of Dermatology” This study reports that Rituximab may be a safe and effective treatment for refractory juvenile systemic lupus erythematosus complicated by macrophage activation syndrome, allowing for successful steroid tapering.