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Men, especially older ones with health issues like prostate cancer, may have worse COVID-19 outcomes and could benefit from therapies targeting male hormones.

Skin diseases linked to insulin resistance should be managed to prevent diabetes and reduce heart disease risk.

5α-reductase inhibitors don't stop bladder cancer from developing or getting worse.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

The flutamide-loaded hydrogel is a promising, skin-friendly treatment for acne and hair loss, potentially requiring less frequent application.

Effective, well-tolerated, and affordable treatments are needed for recurrent ischemic priapism.

Genetic factors affect hair loss, and molecular testing may help predict, diagnose, and treat it.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Riboflavin 5′-phosphate (FMN) shows potential for treating androgen-related conditions but may be limited in treating prostate cancer.

The document concludes that inflammation markers can be used in diabetes, vitamin D3 affects immune pathways, hyperthyroidism changes hormone levels, androgen levels help diagnose Adrenocortical Carcinoma, erectile dysfunction is linked to diabetes, hypogonadism is common in HIV-infected males, and hormones can be biomarkers for various conditions.

Mitoxantrone with a corticosteroid helps manage symptoms for some advanced prostate cancer patients but doesn't extend life.

People with diabetes or obesity should manage their conditions carefully as they have a higher risk of severe COVID-19.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Finasteride helps hair growth but may cause sexual side effects and depression.

Hormones and metabolism play a complex role in prostate enlargement, and more research is needed to improve diagnosis and treatment.

Genetics and hormones play a role in male and female hair loss, but more research is needed to fully understand it.

Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.

Mesenchymal stromal cells may help treat severe COVID-19, but more research is needed to confirm their effectiveness.

PRP treatment may promote hair growth and improve hair density in women with AGA, but more research is needed.

HSD3B1 gene variant and being overweight linked to hair loss in women with polycystic ovary syndrome.

Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.

Testosterone is important for men's sexual function, may help some women's sexual desire, while other hormones and neurotransmitters also play complex roles in sexual behavior.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

COVID-19 might affect male fertility, but more research is needed to understand the full impact.

Sex hormones may affect COVID-19 severity, with men often faring worse, and targeting related pathways could offer treatment options.

Herbal compounds like ricinoleic acid, quercetin-3-O-rutinoside, and hinokiflavone may be safe and effective for treating hair loss.

The conclusion suggests that PCOS may persist due to genetic traits that, while harmful for female fertility, could have provided survival and reproductive benefits to males.

Some men with early hair loss may have a male version of PCOS, affecting hormones and increasing health risks.

A new compound was effective for imaging prostate cancer in rats.

Metformin is less effective in men with early-onset hair loss.