research Control of Hair Follicle Cell Fate by Underlying Mesenchyme Through a CSL–Wnt5a–FoxN1 Regulatory Axis
Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.
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research Delivery and Targeting of Nanoparticles into Hair Follicles
Nanoparticles can improve skin treatments by better targeting hair follicles, but more research is needed for advancement.
research Hair Follicles Contribute Significantly to Penetration Through Human Skin Only Shortly After Application as a Solvent Deposited Solid in Humans
Hair follicles greatly increase caffeine absorption through the skin shortly after it's applied.
research Growth Factors in Hair Organ Development and the Hair Growth Cycle
Growth factors are crucial for hair development and could help treat hair diseases.
research The Keratins of the Human Beard Hair Medulla: The Riddle in the Middle
Human beard hair medulla contains a unique and complex mix of keratins not found in other human tissues.
research Clinical and Neuropathogenetic Aspects of Human African Trypanosomiasis
The document concludes that diagnosing and treating Human African Trypanosomiasis is challenging, but new treatments like fexinidazole are promising.
research Molecular Signaling in Feather Morphogenesis
Feather growth and regeneration involve complex patterns, stem cells, and evolutionary insights.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research KGF And EGF Signaling Block Hair Follicle Induction And Promote Interfollicular Epidermal Fate In Developing Mouse Skin
EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.
research Inherited Ichthyoses: Generalized Mendelian Disorders of Cornification
Inherited ichthyoses cause widespread skin scaling and thickening due to gene mutations.
research Inhibition of SARS-CoV-2 Entry Through the ACE2/TMPRSS2 Pathway: A Promising Approach for Uncovering Early COVID-19 Drug Therapies
Blocking the virus's entry into cells by targeting certain pathways could lead to early COVID-19 treatments.
research Wnt Signaling in Skin Organogenesis
Wnt signaling is crucial for skin and hair development and its disruption can cause skin tumors.
research Exosomal MicroRNAs Derived from Dermal Papilla Cells Mediate Hair Follicle Stem Cell Proliferation and Differentiation
Exosomes from dermal papilla cells help hair growth by making hair follicle stem cells multiply and change.
research The Role of Nuclear Hormone Receptors in Cutaneous Wound Repair
Nuclear hormone receptors play a significant role in skin wound healing and could lead to better treatment methods.
research The Dark Art of Light Measurement: Accurate Radiometry for Low-Level Light Therapy
Most low-level light therapy studies did not accurately report how light was measured, affecting treatment reliability.
research Pediatric Tinea Capitis: Rising Incidence and Treatment
Children with scalp fungal infections need proper diagnosis and treatment, usually with antifungal medications, and newer drugs may offer quicker recovery.
research Epidermal Stem Cells: Practical Perspectives and Potential Uses
Epidermal stem cells could lead to new treatments for skin and hair disorders.
research Potential Targets in the Discovery of New Hair Growth Promoters for Androgenic Alopecia
The document concludes that targeting 5α-reductase, the androgen receptor, and hair growth genes, along with using compounds with anti-androgenic properties, could lead to more effective hair loss treatments.
research Quality of Life in Patients Suffering from Seborrheic Dermatitis: Influence of Age, Gender, and Education Level
Seborrheic dermatitis lowers quality of life more for women, younger people, and those with more education.
research Choreographing Immunity in the Skin Epithelial Barrier
The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.
research Matriptase Activation and Shedding with HAI-1 Induced by Steroid Sex Hormones in Human Prostate Cancer Cells, but Not in Breast Cancer Cells
Steroid sex hormones activate matriptase in prostate cancer cells but not in breast cancer cells.
research Cutaneous Effects of the Most Commonly Used Antidepressant Medication, the Selective Serotonin Reuptake Inhibitors
Antidepressants called SSRIs can cause skin problems, bleeding risk, and other side effects.
research Genetic Defects in Human Pericentrin Are Associated With Severe Insulin Resistance and Diabetes
People with PCNT mutations often develop severe insulin resistance and early-onset diabetes during childhood or adolescence.
research Prolactin Delays Hair Regrowth in Mice
Prolactin slows down hair growth in mice.
research The Antiandrogen Enzalutamide Downregulates TMPRSS2 and Reduces Cellular Entry of SARS-CoV-2 in Human Lung Cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Treatment of Alopecia Universalis with Topical Janus Kinase Inhibitors – A Double Blind, Placebo, and Active Controlled Pilot Study
Topical JAK inhibitors may help treat alopecia universalis by promoting hair regrowth.
research Alopecia Areata Update
Despite progress in treatment, the exact cause of Alopecia areata is still unknown.
research Comparison of Artificial Sebum with Human and Hamster Sebum Samples
Artificial sebum L closely mimics human sebum for drug delivery research.
research Activation of Wnt Signaling in Hematopoietic Regeneration
Wnt10b helps blood stem cells grow after injury.
research Design of Finasteride-Loaded Nanoparticles for Potential Treatment of Alopecia
Finasteride-loaded nanoparticles may help treat alopecia.