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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Higher minoxidil doses in dogs cause faster heart rate, lower blood pressure, and heart issues.

Sp6 promotes tooth development by reducing follistatin levels.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.

Minoxidil does not work to inhibit lysyl hydroxylases in newborn mouse lungs.

The girl's unexpected pubic hair growth led to a diagnosis different from complete androgen insensitivity syndrome.

Minoxidil may work for hair loss by reducing androgen sensitivity and altering hormone-related enzymes.

The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.

Syndecan-1 is essential for maintaining skin fat and preventing cold stress.

Minoxidil and finasteride are the best for non-scarring hair loss; more research is needed for scarring hair loss treatments.

Natural products like plant extracts can help promote hair growth and could be used to treat hair loss.

The research found specific genes and pathways that control fur development and color in young American minks.

The conclusion is that new plant-based treatments for hair loss may work by targeting certain enzymes.

The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

Genetic factors could lead to personalized treatments for hair loss.

Some people experience lasting sexual, psychological, and sleep problems after using finasteride or SSRI antidepressants, possibly due to similar underlying causes.

A new method accurately measures nine specific hormones in human blood.

Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

Minoxidil is processed in the body by an enzyme found in the liver and platelets.

Laser and minoxidil combo promotes better hair growth than minoxidil alone, safely.

Minoxidil helps hair growth by activating enzymes in hair follicles.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Topical minoxidil does not change the activity of hair follicle enzymes that metabolize it.

Tretinoin boosts minoxidil's effect on hair loss by increasing enzyme activity.

A specific enzyme that activates the hair growth medication minoxidil when applied to the skin was identified.