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Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The study developed a tool to predict how gut microbes process foods and drugs, showing that similar compounds often share metabolic pathways and effects.

Dihydrotestosterone can be made from dehydroepiandrosterone in skin cells without needing testosterone.

Potassium channel openers like minoxidil help hair grow by acting on hair follicles.

Combining low-level light therapy and minoxidil 5% is more effective for female hair loss than using either treatment alone.

Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.

Thyroid hormones are important for skin health and might help treat skin diseases, but more research is needed to understand their effects fully.

Higher minoxidil doses in dogs cause faster heart rate, lower blood pressure, and heart issues.

Sp6 promotes tooth development by reducing follistatin levels.

17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.

Common Black hair care products may affect hormone levels and potentially impact health, especially in reproductive and metabolic areas.

Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.

Thyroid hormones affect skin texture, hair and nail growth, and can cause skin diseases related to thyroid problems.

Older rats more affected by minoxidil's cardiotoxic effects than younger rats.

Understanding hair follicle biology and stem cell control could lead to new hair loss treatments.

Over 67 genes linked to ichthyosis help improve diagnosis and treatment.

The enzyme PST is found in developing human kidneys and helps with detoxification and development.

Minoxidil helps protect and rebuild elastic fibers in arteries, improving artery function, especially in older females.

Diagnosing hyperandrogenism in women is complex and requires accurate testing methods and consideration of SHBG levels.

Minoxidil mixed with 2-hydroxypropyl-β-cyclodextrin in water can improve hair growth more than minoxidil alone.

CAH is a genetic disorder affecting cortisol production and causing hormonal imbalances, with treatment and diagnosis varying by form and symptoms.

The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.

Rare adrenal cancers that secrete androgens or estrogens have a poor prognosis and are treated primarily with surgery.

PRP therapy and minoxidil combo works best for male hair loss.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Finasteride effectively lowers specific hormone levels, helping monitor treatment progress.

Testosterone significantly affects sexual desire in both men and women, but its impact on women is more complex and influenced by psychological factors.

Minoxidil with tretinoin boosts hair growth most effectively, followed by minoxidil alone, and then ketoconazole.

Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.

DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.