Canine Sertoli Cell Tumor: Anti-Müllerian Hormone, Inhibin B, and Estrone Sulphate
April 2023
in “
Clinical theriogenology
”
TLDR The dog's skin condition improved after removing a tumor that was causing hormone imbalances.
A male boxer dog with chronic generalized alopecia and pruritus was diagnosed with a Sertoli cell tumor (SCT) associated with cryptorchidism. The diagnosis was supported by physical symptoms, penile/preputial cytology, ultrasonography, and elevated serum anti-Müllerian hormone (AMH) and inhibin B levels. After surgical removal of the tumor, the dog's AMH levels dropped from 8,435 to 56 ng/ml, and inhibin B levels decreased from 805 to less than 6 pg/ml. The dog showed improvement in dermatoses and reduced nipple enlargement two months post-surgery. This case demonstrates the usefulness of various diagnostic procedures in identifying SCT and cryptorchidism in dogs with skin conditions.
