This study uncovered how Staphylococcus hominis transports an odor precursor molecule, potentially leading to new ways to control body odor production in humans.
26 citations
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June 2024 in “Frontiers in Immunology” The authors discussed that SOCS1 and SOCS3's inhibition of JAKs plays a significant role in the development of JAK inhibitor drugs for skin inflammatory diseases and malignancies.
32 citations
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December 2015 in “PloS one” This study found that applying a topical inhibitor of TGF-β1 may enhance scar maturation and improve the appearance of hypertrophic scars in a nude mouse model after two weeks.
7 citations
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December 2024 in “Antibiotics” This review discusses the potential of cathelicidins in treating skin conditions but highlights significant challenges, including unclear clinical efficacy, safety concerns, and bacterial resistance, that must be addressed for successful medical application.
25 citations
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May 2017 in “InTech eBooks” This review details the diverse catalytic activities of abzymes in systemic lupus erythematosus (SLE) and reports no new experimental findings; it discusses the impact of these abzymes on disease pathogenesis.
6 citations
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August 2024 in “Advanced Science” This study presents a Cu-catalyzed atroposelective method achieving high stereoselectivity for synthesizing chiral biaryl N-oxides, with product 3e showing promising therapeutic efficacy against triple-negative breast cancer in cell lines MDA-MB-231 and MDA-MB-468.
4 citations
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September 2025 in “Pharmaceutics” This review highlights the potential of natural hydrogels as advanced wound dressings, emphasizing their capabilities in mimicking the extracellular matrix, supporting healing, and delivering therapeutic agents for chronic and infected wound care.
4 citations
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June 2025 in “MedComm” This review detailed the significant progress and challenges in the design and application of PROTACs, a novel class of cancer therapeutics, highlighting their clinical trials, design complexities, and the role of artificial intelligence in improving their efficacy and selectivity for cancer therapy.
2 citations
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November 2023 in “Journal of Natural Products” In this study, researchers accomplished the total synthesis of calanthoside, noted for its strong proliferative effects on human hair follicle dermal papilla cells, using a seven-step process from anthranilic acid with a 43% overall yield.
January 2025 in “Catalysts” This study investigated the production of β-cyclodextrin from ginkgo seeds, finding that a pretreatment scheme involving high-temperature gelatinization significantly improved the conversion rate to 72.63%, highlighting the industrial potential of underutilized ginkgo seed powder for sustainable applications.
October 2024 in “Frontiers in Immunology” This study proposes that intranasal exposure to PTx and autoantigen in an animal model can trigger autoimmune disease, supporting the idea that subclinical nasal colonization by BP may cause alopecia areata.
48 citations
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January 2024 in “Frontiers in Pharmacology” This paper reviews strategies to enhance the effectiveness of topical drug delivery by addressing skin barrier challenges, optimizing drug delivery systems, and personalizing treatment approaches, highlighting both current advancements and limitations in the field.
March 2026 in “Journal of Investigative Dermatology” Genetic factors, especially PADI3 gene variants, contribute to CCCA in women of African descent.
172 citations
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March 2019 in “The EMBO Journal” This study found that in Arabidopsis thaliana, the interaction between extracellular leucine-rich repeat extensins and the receptor-like kinase FERONIA helps control vacuolar expansion, crucial for cellular elongation.
82 citations
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July 2022 in “Bioengineering & Translational Medicine” This review examines how biochemical and biophysical induction factors influence cell fate in tissue engineering and reports no new experimental results.
34 citations
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April 2012 in “Molecular Biology Reports” This study isolated a thermophilic bacterial strain, Bacillus cereus, from soil that produces an extracellular protease; the enzyme effectively removed non-leather structures from animal pelts and was compatible with commercial detergents.
28 citations
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September 1998 in “Journal of Investigative Dermatology” This study isolated and characterized two distinct types of caspase-like proteases from human epidermis, suggesting their involvement in keratinocyte differentiation and apoptosis processes.
22 citations
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December 2020 in “mSphere” This study identified a fungal sulfotransferase enzyme, FgSULT1, from *Fusarium graminearum*, expanding the sulfotransferase superfamily and offering new biocatalytic methods for producing bioactive sulfates.
16 citations
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June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that DHHC13 is crucial for hair anchoring and skin barrier function, with its deficiency in Zdhhc13(skc4) mice leading to cyclic alopecia and skin abnormalities due to cornifelin deficiencies.
6 citations
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November 2024 in “Frontiers in Sustainable Food Systems” This study found that ultrasonication pre-treatment at various power levels improved the color, protein solubility, and degree of hydrolysis of fish protein hydrolysates from mackerel side streams, and potentially reduced bitterness by decreasing hydrophobic free amino acids.
6 citations
,
February 2023 in “Biomaterials Research” This review explores the different types of hydrogels used to repair diabetic ulcers, the mechanisms involved, and the limitations in developing these technologies for clinical use, but it reports no new clinical results.
3 citations
,
December 2021 in “Recent patents on anti-cancer drug discovery” This review examines the role of SET7/9 in non-histone methylation and its implications in various diseases, including cancer, but presents no new clinical results.
13 citations
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April 2021 in “International Journal of Molecular Sciences” This study found that the fermented black soybean product GR-SC65 reduced particulate matter-induced cell death and oxidative stress in A549 cells, suggesting potential as a therapeutic agent for lung injury prevention.
2 citations
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July 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that blocking autophagy in Atg7-deficient mouse hair keratinocytes altered the molecular composition of hair shafts by increasing the abundance of proteins involved in protein turnover while keratins remained unchanged, highlighting autophagy's role in reducing non-cytoskeletal protein concentrations in hair.
January 2026 in “Experimental Dermatology” This review discusses the role of keratinocytes in hidradenitis suppurativa, highlighting their genetic and metabolic influences on disease progression without presenting new clinical results.
97 citations
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May 2019 in “Frontiers in Cell and Developmental Biology” This review examines the interaction between the extracellular matrix and immune cells in skin diseases and evaluates advanced therapies that target involved molecular mechanisms, reporting no new clinical findings.
This review summarizes recent genetic research on hidradenitis suppurativa, highlighting potential therapeutic targets and genetic mutations, but reports no new clinical findings.
3 citations
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November 2014 in “Protein Expression and Purification” This study reported successful recovery of biologically active recombinant murine Wnt3a without detergent, suggesting usefulness for structure-activity studies avoiding detergent-related issues.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” This study identified a novel mechanism by which dsRNA-induced TLR3 activation and retinoic acid pathways contribute to new hair follicle formation after deep wounds in mice and suggested a similar potential in humans.
23 citations
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January 2012 in “International Food Research Journal” This case report describes a 39-year-old woman whose dermatomyositis-systemic lupus erythematosus overlap syndrome symptoms resolved after switching to tofacitinib.