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Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Insulin resistance and obesity are key factors in the development and worsening of polycystic ovary syndrome, and lifestyle changes are important for managing it.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.

Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.

Men are more likely to have severe COVID-19 cases and fatalities than women due to factors like lifestyle, aging, and biological differences.

Skin cells produce and activate vitamin D, which regulates skin functions and supports hair growth.

Special fiber materials boost the healing properties of certain stem cells.

Bone Morphogenetic Proteins (BMPs) help control skin health, hair growth, and color, and could potentially be used to treat skin and hair disorders.

Capsaicin, found in chili peppers, can slow down hair growth by affecting skin cells and hair follicles.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

Pectin biosynthesis is essential for the growth of cotton fibers and Arabidopsis root hairs.

Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.

Stress-related substance P may lead to hair loss and negatively affect hair growth.

TGF-β is crucial for controlling stem cell behavior and changes in its signaling can lead to diseases like cancer.

Using CDK inhibitors on rats showed a reduction in chemotherapy-caused hair loss, but later experiments could not repeat these results.

Researchers developed promising agents for prostate cancer imaging, with the best one showing high potential for clinical use.

Cathepsin L is essential for normal hair growth and development.

The WNT signaling pathway is important in many diseases and targeting it could offer new treatments.

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

Eating less sugar, milk, and saturated fats and more vegetables and fish may help treat and prevent acne.

The conclusion is that PCOS is caused by ovarian sensitivity to hormones and disrupted hormone control, possibly due to ovarian factors, and more research is needed.

Macrophages help heal nerves by aiding the maturation of Schwann cells and are important for nerve repair.

Prolactin contributes to hair loss by promoting hair follicle shrinkage and cell death.

Fat cells in the skin help start healing and form important repair cells after injury.

New targets for making and using brain-synthesized steroids could lead to better treatments for brain disorders and alcoholism.

Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.

Eclipta alba extract may help hair grow similarly to Minoxidil.

Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.