Unravelling the Threads of Central Centrifugal Cicatricial Alopecia
March 2026
in “
Journal of Investigative Dermatology
”
Research cited in this study
6 / 6 resultsresearch Pathogenic Variants Affecting Peptidyl Arginine Deiminase 3 and Its Major Substrates Underlie Central Centrifugal Cicatricial Alopecia
Genetic variants in specific genes cause central centrifugal cicatricial alopecia.
research A Hairy Situation: PADIs in Regeneration and Alopecia
Enzymes called PADIs play a key role in hair growth and loss.
research Human Hair Follicles Operate an Internal Cori Cycle and Modulate Their Growth via Glycogen Phosphorylase
Inhibiting glycogen metabolism can promote hair growth.
research Association of Breast and Colorectal Cancer in Patients With Central Centrifugal Cicatricial Alopecia: A Retrospective, Cross-Sectional Pilot Study
Patients with central centrifugal cicatricial alopecia may have a higher risk of breast and colorectal cancer.
research Variant PADI3 in Central Centrifugal Cicatricial Alopecia
Mutations in the PADI3 gene are linked to a higher risk of scarring hair loss in women of African descent.
research The Fate of Trichohyalin
Trichohyalin is modified by enzymes to form strong structures in hair cells.