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330-360 / 1000+ resultsresearch Expanding on the phenotypic spectrum of Woodhouse‐Sakati syndrome due to founder pathogenic variant in DCAF17: Report of 58 additional patients from Qatar and literature review
This study on Qatari patients with Woodhouse-Sakati syndrome highlights the high incidence and diverse clinical presentation due to a specific genetic variant, emphasizing early diagnosis for effective management.
research Health-related quality of life with sacituzumab govitecan in HR+/HER2− metastatic breast cancer in the phase III TROPiCS-02 trial
This study found that sacituzumab govitecan improved health-related quality of life in most areas for patients with HR+/HER2− metastatic breast cancer compared to chemotherapy, except for increased diarrhea, supporting its use as a treatment option.
research Postural orthostatic tachycardia syndrome: a dermatologic perspective and successful treatment with losartan.
This case report details a woman with postural orthostatic tachycardia syndrome who experienced notable dermatological symptoms, including evanescent hyperemia, which improved with the use of an oral angiotensin II type 1 receptor antagonist.
research CRYSTAL STRUCTURE OF HSIANGHUALITE
This article suggests that testosterone therapy might be considered if other treatments fail, but emphasizes discussing potential risks and benefits with patients before prescribing.
research 490 Samcyprone (diphenylcyclopropenone ointment) for the treatment of common warts
This phase 2a trial evaluated Samcyprone for common wart treatment and found that while a sensitization reaction is necessary for therapeutic response, its level does not predict wart clearance.
research Sexual transmission of a new emerging dermatophyte: T. Mentagrophytes genotype VII
This study highlights that Trichophyton mentagrophytes genotype VII, primarily transmitted sexually among men who have sex with men, has established itself in Europe, necessitating awareness and surveillance to prevent its spread.
research Serial Excision Technique to Reduce Cicatricial Alopecia
This source reports that SET may offer notable cosmetic improvements and enhance well-being for patients with CA, serving as a cost-effective treatment option either alone or alongside hair transplantation.
research Transsexualism
This article reviews treatment processes and outcomes for transsexualism, reporting improved quality of life and reduced gender dysphoria post-gender reassignment, though increased psychiatric risks remain compared to the general population.
research A Consensus Single-cell Atlas Of Hidradenitis Suppurativa Tunnels Defines A Fibro-inflammatory Niche With Druggable Microenvironmental Endotypes
This study constructed a consensus single-cell atlas of hidradenitis suppurativa tunnels, identifying distinct microenvironmental endotypes with different inflammatory and fibrotic profiles, suggesting that TNF blockade may not be sufficient for addressing all lesions.
research Exploring the Dermoscopic Patterns in Tuberous Sclerosis
This study examined the dermoscopic features of five patients with tuberous sclerosis and found that dermoscopy can differentiate characteristic cutaneous features from similar conditions, potentially aiding in earlier diagnosis when other symptoms are subtle or absent.
research Loss of epidermal Evi/Wls results in a phenotype resembling psoriasiform dermatitis
This study found that Wnt secretion is important for maintaining skin homeostasis in mice, as Evi-deficient mice developed psoriasis-like skin lesions and had an imbalance in immune cell populations.
research Commonly Misdiagnosed Rare Condition – Toe Tourniquet Syndrome – Literature Review
This review discusses Toe Tourniquet Syndrome, a frequently misdiagnosed condition that can lead to necrosis if untreated, and calls for increased clinician awareness, but reports no new clinical findings.
research Towards a consensus potency assay for mesenchymal stromal cells: a matrix analysis of cell source, donor variability and inflammatory stimuli to refine surrogate markers of immunomodulation
In this study, only a subset of proposed biomarkers universally responded to priming in mesenchymal stromal cells, suggesting limited utility for standardized potency assays across different MSC types and conditions.
research Standards of Care for the Health of Transsexual, Transgender, and Gender-Nonconforming People, Version 7
This publication reviews the World Professional Association for Transgender Health's Standards of Care for supporting transgender and gender nonconforming people, with adjustments needed for diverse global contexts and no new clinical results.
research S87 Image guided radiotherapy (IGRT) in stage III prostate cancer: analysis of acute toxicity
This study demonstrates that a new Adaptive Modulation and Coding method can improve control performance in Communication-Based Train Control systems using WLAN by reducing average delay through effective transmission mode selection.
research A Consensus Single-cell Atlas Of Hidradenitis Suppurativa Tunnels Defines A Fibro-inflammatory Niche With Druggable Microenvironmental Endotypes
This study constructed a consensus single-cell atlas for hidradenitis suppurativa tunnels, identifying distinct fibro-inflammatory microenvironments with potential drug targets, suggesting TNF blockade alone may not be effective for all lesion types.
research Scalp Medical Tattooing Technique to Camouflage Bifid Parietal Whorls
This study found that scalp medical tattooing effectively improved cosmetic appearance and concealed bifid parietal whorls without complications in the patients evaluated.
research Nematic Fibrin Fibers Enabling Vascularized Thrombus Implants Facilitate Scarless Cutaneous Wound Healing
In this study, implantable vascularized engineered thrombi using autologous whole blood improved skin wound healing in rats by promoting robust microcapillary networks and accelerating healing processes.
research The Monophenolic Antioxidant TS-13 Accelerates Hair Restoration in Mice with Chemotherapy-Induced Alopecia
The researchers reported that administration of the antioxidant compound TS-13 in mice with chemotherapy-induced alopecia accelerated hair regrowth, although it did not fully prevent chemotherapy-related hair loss, suggesting TS-13 may aid in managing hair loss without negating the cancer treatment's effectiveness.
research Forthcoming Issues
This study found that white wax and its extract significantly promoted hair growth in a mouse model of androgenetic alopecia, outperforming finasteride by inhibiting 5α-reductase activity and enhancing cellular proliferation.
research The Role of dWAT ‐Immune Crosstalk in Hair Follicle Microenvironment in Hair Regeneration
In this review, the authors summarize recent findings on dermal white adipose tissue (dWAT), highlighting its crucial role in the hair follicle microenvironment by regulating inflammation and immune responses, thus influencing hair regeneration.
research The fretful child with swollen appendage: Mitten the Insidious
This article reports a case of hair tourniquet syndrome in a child's toe, successfully treated surgically, and emphasizes the need for healthcare providers to be aware for early detection and treatment.
research Daily subcutaneous testosterone for management of testosterone deficiency
This retrospective analysis reported significant increases in testosterone levels in men with testosterone deficiency using the Daily Subcutaneous Testosterone method combined with hCG and anastrozole, indicating its potential as a treatment option.
research CuATSM Enhances Wound Repair Without Scarring via Hippo/YAP Signalling Pathway to Reduce Ferroptosis and Macrophage Polarisation
This study using a mouse model reports that CuATSM treatment accelerates skin wound healing and reduces scar formation, with effects possibly mediated via the ferroptosis-induced Hippo/YAP signaling pathway and macrophage polarization, suggesting CuATSM as a potential therapy for scarless wound healing in clinical settings.
research Experience of Professor WEI Yue-gang Treating Androgenic Alopecia
This paper discusses Professor WEI Yue-gang's approach to treating androgenetic alopecia with Traditional Chinese Medicine and reports no new clinical results.
research Tetrahydroxystilbene Glucoside Effectively Prevents Apoptosis Induced Hair Loss
This study found that topical application of TSG from Polygonum multiflorum promoted hair regrowth in depilated mice, potentially through the inhibition of apoptosis-related proteins.
research titanflow
This report discusses Titanflow as a potential improvement in male urinary health by focusing on the detrusor muscle rather than prostate size, suggesting it may offer relief where other supplements have limited effectiveness.
research A Correlative Fluorescent and Electron Microscopic Technique for Ultralocalization of Trichocyte Keratins
This study demonstrates a sample preparation method for wool follicles that allows for clear keratin labeling and ultrastructural preservation in microscopy, reducing common artefacts from conventional fixation techniques.
research Advancements in Therapeutic Deep Eutectic Solvents as Multifunctional Transdermal Delivery Systems
This review discusses therapeutic deep eutectic solvents as promising "green" solutions for enhancing drug solubility and delivery through the skin, reporting no new clinical results and highlighting future research directions.