The Monophenolic Antioxidant TS-13 Accelerates Hair Restoration in Mice with Chemotherapy-Induced Alopecia

    January 2026 in “ Cell and Tissue Biology ”
    E. B. Menshchikova, A. E. Serykh, L. P. Romakh … N. V. Kandalintseva
    Studysummary The researchers reported that administration of the antioxidant compound TS-13 in mice with chemotherapy-induced alopecia accelerated hair regrowth, although it did not fully prevent chemotherapy-related hair loss, suggesting TS-13 may aid in managing hair loss without negating the cancer treatment's effectiveness.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on link.springer.com →
    Discuss this study in the Community →

    Research cited in this study 12

    1. Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients Nutrients · 2025
    2. Original Synthetic Monophenolic Antioxidant with Combined Effect Inhibits Tumor Growth In Vivo Сибирский научный медицинский журнал · 2025
    3. The Role of Minoxidil in the Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis Journal of Clinical Medicine · 2024
    4. Low-Level Laser And LED Therapy In Alopecia: A Systematic Review And Meta-Analysis Dermatologic Surgery · 2024
    5. Chemotherapy-Induced Alopecia by Docetaxel: Prevalence, Treatment, and Prevention Current Oncology · 2024
    6. Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming? Current Oncology · 2023
    7. Mild Oxidative Stress Protects Against Chemotherapy-Induced Hair Loss Frontiers in Oncology · 2023
    8. Low Intensity Ultrasound as an Antidote to Taxane/Paclitaxel-Induced Cytotoxicity Journal of Cancer · 2022
    9. The Side Effects of Platinum-Based Chemotherapy Drugs: A Review for Chemists Dalton transactions · 2018
    10. Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond? BioEssays · 2017
    11. Preventive Effects of Cedrol Against Alopecia in Cyclophosphamide-Treated Mice Environmental Toxicology and Pharmacology · 2016
    12. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005