The Dual-Action Monophenolic Antioxidant TS-13 Accelerates Hair Coat Restoration in a Mouse Model of Chemotherapy-Induced Alopecia

    November 2025 in “ Сибирский научный медицинский журнал ”
    E. B. Menshchikova, A. E. Serykh, L. P. Romakh … Н. В. Кандалинцева
    Studysummary In this study, TS-13, an antioxidant, accelerated hair regrowth in a mouse model of chemotherapy-induced alopecia but did not completely prevent cyclophosphamide's hair loss effects, showing potential for mitigating such side effects without interfering with the drug's therapeutic action.
    Automatically generated from the study's abstract, not written by a person, and not a review of the full paper. Not medical advice or a treatment recommendation. Read the original study, and consult a qualified healthcare professional before changing treatment. Full disclaimer
    Read the full study on sibmed.elpub.ru →
    Discuss this study in the Community →

    Research cited in this study 11

    1. Safety First: A Comprehensive Review of Nutritional Supplements for Hair Loss in Breast Cancer Patients Nutrients · 2025
    2. Original Synthetic Monophenolic Antioxidant with Combined Effect Inhibits Tumor Growth In Vivo Сибирский научный медицинский журнал · 2025
    3. The Role of Minoxidil in the Treatment of Alopecia Areata: A Systematic Review and Meta-Analysis Journal of Clinical Medicine · 2024
    4. Low-Level Laser And LED Therapy In Alopecia: A Systematic Review And Meta-Analysis Dermatologic Surgery · 2024
    5. Prevention and Treatment of Chemotherapy-Induced Alopecia: What Is Available and What Is Coming? Current Oncology · 2023
    6. Mild Oxidative Stress Protects Against Chemotherapy-Induced Hair Loss Frontiers in Oncology · 2023
    7. Low Intensity Ultrasound as an Antidote to Taxane/Paclitaxel-Induced Cytotoxicity Journal of Cancer · 2022
    8. The Side Effects of Platinum-Based Chemotherapy Drugs: A Review for Chemists Dalton transactions · 2018
    9. Oxidative Stress Management in the Hair Follicle: Could Targeting NRF2 Counter Age-Related Hair Disorders and Beyond? BioEssays · 2017
    10. Preventive Effects of Cedrol Against Alopecia in Cyclophosphamide-Treated Mice Environmental Toxicology and Pharmacology · 2016
    11. A Guide to Assessing Damage Response Pathways of the Hair Follicle: Lessons From Cyclophosphamide-Induced Alopecia in Mice Journal of Investigative Dermatology · 2005