This study in diabetic db/db mice found that treatment with the antihypertensive agents minoxidil or nebivolol stimulated elastogenesis and inhibited elastolysis, leading to restored elastic fibers, reduced aortic stiffening, and normalized blood pressure.
April 2024 in “Cellular signalling” This study on mice found that activating TRPML channels with MLSA1 promoted hair regeneration, accelerated hair cycle transition, and influenced human dermal papilla cells to secrete hair growth promoting factors while reducing hair growth inhibitors and oxidative damage.
February 2024 in “Current Medicinal Chemistry” In this study, minoxidil nanoparticles significantly increased hair growth rate in C57BL/6 mice compared to traditional minoxidil, suggesting enhanced effectiveness and potential as a new formulation.
October 2023 in “Clinical medicine and medical research” This study indicates that higher thyroid-stimulating hormone levels may be linked to post-COVID-19 hair loss in women, while ferritin levels showed no significant correlation.
October 2023 in “Journal of the Endocrine Society” This case report describes a challenging diagnosis of Cushing’s syndrome using endocrine tests and imaging, which ultimately identified an adrenal etiology. Successful treatment involved a non-invasive desmopressin stimulation test and right adrenalectomy, leading to improvement in symptoms and health outcomes for the patient.
May 2020 in “Meeting abstracts/Meeting abstracts (Electrochemical Society. CD-ROM)” This research reported that using an electromechanical system based on flexible nanogenerators significantly accelerated skin wound healing and hair growth, and reduced food intake in rat models.
April 2019 in “Journal of Investigative Dermatology” This study demonstrates that DHT-induced lipid synthesis in sebocytes involves the mTOR pathway, suggesting mTOR inhibitors may help modulate androgen-dependent sebum overproduction.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” In this study, IL-1α and IL-7 were found to work together to activate epidermal γδ T-cells, which in turn promote hair follicle stem cell proliferation during mouse wound healing.
Processed fat, SVF, and PRP are safe and effective for facial rejuvenation and hair growth.
April 2017 in “Leukemia research” This study reported that tofacitinib may be a promising treatment for alopecia areata in adolescents, showing significant hair regrowth with mild adverse effects in a retrospective review.
July 2014 in “Acupuncture & electro-therapeutics research” This study observed that certain changes in facial "heart representation areas," like eyebrow hair whitening and loss, are associated with cardiovascular issues and may correspond with increased Cardiac Troponin I levels.
105 citations
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February 2010 in “Endocrinology” This study found that normal human epidermis expresses TSH and may be an indirect target of TSH signaling, with expression regulated by endocrine controls of the hypothalamic-pituitary-thyroid axis.
14 citations
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September 2018 in “International Journal of Molecular Sciences” This study found that mackerel-derived fermented fish oil extract and its component DHA promote hair growth by activating anagen pathways in dermal papilla cells.
7 citations
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December 2006 In this study, oral Tribulus terrestris extract significantly increased MSH expression in mouse hair follicle melanocytes, suggesting enhanced melanocyte activity and migration.
5 citations
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January 2014 in “Molecular Simulation” This study discovered a potential new 5α-reductase type II inhibitor with higher predicted activity than finasteride, suggesting it as a promising candidate for treating benign prostatic hyperplasia.
February 2026 in “South Asian Research Journal of Biology and Applied Biosciences” In this study, patients with alopecia areata had significantly higher levels of luteinizing hormone and follicle-stimulating hormone compared to healthy controls, suggesting a link between hormone levels and the disease.
This simulation study found that higher cannabis exposure in a virtual population was associated with increased hair shedding severity and reduced follicular density, but these results are based on modeled data and cannot establish causal relationships.
July 2024 in “International Journal of Chemical and Biological Sciences” This study reported that women with polycystic ovary syndrome had higher glypican-4 levels compared to controls, indicating its significant role in hormonal regulation associated with the condition.
November 2023 in “International Journal of Trichology” This study, conducted at a tertiary care hospital, found no statistically significant association between male pattern hair loss and levels of serum ferritin or thyroid-stimulating hormone, suggesting these factors may not play a role in this condition.
March 2014 in “Journal of The American Academy of Dermatology” Vitamin D deficiency is common in temporary hair loss, and stress is often a suspected cause.
6 citations
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January 2015 in “Journal of The European Academy of Dermatology and Venereology” This review examines various conditions that resemble androgenetic alopecia, analyzing their pathogenesis and highlighting the difficulties they pose for accurate diagnosis and treatment; it reports no clinical results.
81 citations
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February 1997 in “Journal of Investigative Dermatology” This study suggests that minoxidil activates PGHS-1, which may explain its hair growth-stimulating effects and could aid in designing more potent hair growth-promoting drugs.
52 citations
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September 2017 in “Current Stem Cell Research & Therapy” This review examines the effects of adipose-derived stem cells and their secreted factors on hair growth stimulation in laboratory and animal models, suggesting their potential as therapeutic agents for hair loss treatment.
31 citations
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March 2010 in “Molecular Endocrinology” This study identified that androgens increase calcium sensitization in mouse colonic smooth muscle by activating the Rho/Rho kinase pathway, highlighting its role in modulating muscle contractility.
28 citations
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July 2002 in “Australasian Journal of Dermatology” This case report describes a 27-year-old woman with lupus erythematosus whose biopsy findings indicated that lupus panniculitis can mimic alopecia areata, leading to temporary hair loss.
24 citations
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September 2005 in “Journal of Cellular Biochemistry” This study found that all-trans and 9-cis retinoic acids increase steroid sulfatase activity in HL60 cells through mechanisms involving RARα/RXR heterodimers and multiple signaling pathways.
23 citations
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December 2008 in “Current medicinal chemistry” This study reports that stimulating sensory neurons with capsaicin and isoflavone increases IGF-I production, promoting hair growth in mice and human volunteers with alopecia.
21 citations
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January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” In this study, researchers demonstrated that in a mouse model, the stimulation of mammary tumor growth due to progesterone is primarily caused by its metabolite, 5αP, not progesterone itself.
18 citations
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February 2023 in “Plants” This study found that PES1CMU-defatted rice bran (DFRB) showed effective skin whitening and anti-aging properties comparable to standard treatments in cell models, suggesting its potential use in dermatocosmetics.
16 citations
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April 2021 in “International Journal of Molecular Sciences” This study found that micro-current electrical stimulation may promote hair growth in human hair follicle-derived papilla cells and a mice model by enhancing cell proliferation, migration, and activating key growth pathways.