Autophagy Stimulation Improves Erythroid Proliferative Capacity in Models of SF3B1 Mutant MDS

    April 2017 in “ Leukemia research ”
    Valeria Visconte, Vera Ademà, Yasmine Hirbawi, Bartlomiej Przychodzen, Katherine A. Kelly, Cassandra M. Hirsch, Michael J. Clemente, Suresh Kumar Balasubramanian, Hetty E. Carraway, Daniel J. Lindner, Mikkael A. Sekeres, Heesun J. Rogers, James G. Phillips, T. Radivoyevitch, Steffan T. Nawrocki, Jennifer S. Carew, J. Maciejewski
    From the encyclopedia
    Alopecia Areata →

    autoimmune disorder causing patchy hair loss

    Tofacitinib →

    a JAK inhibitor for alopecia areata and other autoimmune conditions

    Studysummary This study reported that tofacitinib may be a promising treatment for alopecia areata in adolescents, showing significant hair regrowth with mild adverse effects in a retrospective review.
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